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Growth and Neurodevelopmental Outcomes at 12 to 18 Months of Corrected Age in Preterm Infants Born Small for Gestational Age

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Abstract

Objective

To compare the growth and neurodevelopmental outcomes at 12 to 18 months of corrected age in preterm infants (gestation 35 wks) born appropriate for gestation (AGA) with those born small for gestation (SGA).

Methodology

This cross sectional, study assessed the growth outcomes in terms of underweight, stunting, microcephaly, overweight and obesity. Development delay was defined as developmental quotient 70 on DASII.

Results

Out of 178 infants enrolled in the study 119 were AGA and 59 were SGA. The mean gestational age of the study cohort was 30.45 (2.08) weeks. More infants in the SGA group were underweight (59.3% vs. 37.8%, RR: 1.79, 95% CI: 1.16–2.74), stunted (62.7% vs. 30.25%, RR: 2.19, 95% CI: 1.42–3.36) and had higher incidence of motor (6.7% vs.0.8%, RR: 2.5, 95% CI: 1.5–4.1) and mental development (3% vs. 0, RR: 3.1, 95% CI: 2.5–3.8) delay.

Conclusion

Preterm SGA infants are at an increased risk of underweight, stunting, motor and mental development delay when compared with preterm AGA infants in early childhood.

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Funding

Funding: None

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Authors and Affiliations

  1. Department of Neonatology, Fernandez Hospital, Hyderabad, Andhra Pradesh, India

    Srinivas Murki, Venkat Reddy Kallem, Jaishree Gururaj, Tanveer Bashir, Tejo Pratap Oleti & Sai Kiran

Authors
  1. Srinivas Murki
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  2. Venkat Reddy Kallem
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  3. Jaishree Gururaj
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  4. Tanveer Bashir
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  5. Tejo Pratap Oleti
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  6. Sai Kiran
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Contributions

Contributors: VRK: data collection, analysis and prepared the manuscript; SK: data collection and data analysis and review of manuscript; JG, TB: development assessment and data collection; SM: preparation of protocol, analysis, writing and review of manuscript.

Corresponding author

Correspondence to Srinivas Murki.

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Competing Interest: None stated.

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Murki, S., Kallem, V.R., Gururaj, J. et al. Growth and Neurodevelopmental Outcomes at 12 to 18 Months of Corrected Age in Preterm Infants Born Small for Gestational Age. Indian Pediatr 57, 301–304 (2020). https://doi.org/10.1007/s13312-020-1779-9

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  • DOI: https://doi.org/10.1007/s13312-020-1779-9

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