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Acid Suppression in Neonates: Friend or Foe?

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Abstract

Medications that reduce gastric acid secretion are commonly prescribed for treating gastroesophageal reflux disease. However, several studies have shown that these medications are not very effective, and are associated with adverse effects. This article discusses the physiology of gastric acid secretion, clinical indications and pharmacology of acid suppressing medications, and possible adverse effects of these medications.

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Funding

Funding: None; Competing interests: None stated.

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Authors and Affiliations

  1. Department of Pediatrics, University of Calgary, Calgary, Canada

    Prashanth Murthy & Abhay Lodha

  2. Department of Community Health Sciences, University of Calgary, Calgary, Canada

    Aliyah Dosani & Abhay Lodha

  3. School of Nursing and Midwifery, Mount Royal University, Calgary, Canada

    Aliyah Dosani

  4. Department of Pediatrics, and Community Health Sciences, Foothills Medical Centre, C211, 29th Street NW, Calgary, Alberta, Canada, T2N 2T9

    Abhay Lodha

Authors
  1. Prashanth Murthy
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  2. Aliyah Dosani
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  3. Abhay Lodha
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Correspondence to Abhay Lodha.

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Murthy, P., Dosani, A. & Lodha, A. Acid Suppression in Neonates: Friend or Foe?. Indian Pediatr 56, 541–546 (2019). https://doi.org/10.1007/s13312-019-1549-8

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  • DOI: https://doi.org/10.1007/s13312-019-1549-8

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