Abstract
Aim
To determine the correlation between vitamin D levels and gestational diabetes mellitus.
Materials and Methods
Cross-sectional observational study, conducted in Gauhati Medical College and Hospital, over a period of 1Â year, on 350 antenatal patients, with gestational age beyond 24Â weeks, keeping in mind the inclusion and exclusion criteria. Age, obstetric score, religion, BMI were noted for all patients. They underwent screening for gestational diabetes mellitus using DIPSI (Diabetes in Pregnancy Study Group of India) guidelines and were divided into two groups. Vitamin D estimation by CLIA method (chemiluminescence method) was done in both groups and results were compared. Association between vitamin D levels and gestational diabetes mellitus was studied using Chi Square Test.
Results
The prevalence of vitamin D deficiency in antenatal patients was found to be 63.7%. 73% of gestational diabetes mellitus patients were deficient in vitamin D. There was a statistically significant association seen between vitamin D level and Gestational diabetes mellitus (p value—0.046). There was 1.34 times increased risk of developing gestational diabetes mellitus when the vitamin D levels were deficient as compared to when the vitamin levels were within the normal range.
Conclusion
There was a high level of vitamin D deficiency in the pregnant women of North East. Due to lack of screening of vitamin D levels, many pregnant women suffer from adverse feto-maternal outcomes. There is a need to identify them early in pregnancy, provide vitamin D supplementation and to decrease the likelihood of them developing complications.
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Funding
This study was funded by the Janani Shishu Suraksha Karyakram (JSSK) program. The lab tests done were free of cost to the patients.
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The Study was performed in line with the principles of the declaration of Helsinki. Before conducting the study, a synopsis was submitted to the Institutional Ethical Committee of Gauhati Medical College and Hospital and approval was granted for the same on 26/7/2021. (Order number – MC/190/2007/Pt-II/July – 2021/TH-46) A written informed consent has been obtained from the subjects after full explanation of the requirement of the study.
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Bishnu Prasad Das is a Professor; Sasindra Kumar Das is an Assistant Professor; Ashok Krishna Bhuyan is an Associate Professor; Aishwarya Nandakumar is a Resident Surgeon.
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Das, B.P., Das, S.K., Bhuyan, A.K. et al. Relationship Between Vitamin D Level and Gestational Diabetes Mellitus: A Cross-Sectional Study. J Obstet Gynecol India 73 (Suppl 1), 83–87 (2023). https://doi.org/10.1007/s13224-023-01832-1
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DOI: https://doi.org/10.1007/s13224-023-01832-1