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Primary Peritoneal Rhabdomyosarcomatosis in a 2-Year-Old Child Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy — Case Report and Review of Literature

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Abstract

Pediatric peritoneal sarcomatosis is an exceedingly rare entity with unknown incidence. Within these tumors, primary peritoneal rhabdomyosarcoma constitutes a small fraction. Majority of them are probably treated inadequately and have dismal outcomes. A favorable subset exists where aggressive treatment in the form of cytoreductive surgery supplemented by hyperthermic intraperitoneal chemotherapy in the multimodal setting can be attempted. We present a case of primary peritoneal embryonal rhabdomyosarcoma in a 2-year-old child who was treated with systemic chemotherapy, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy while avoiding radiation, with its evidence and rationale.

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Data Availability

All data was retrieved from electronic medical records of the hospital.

Abbreviations

CECT:

Contrast-enhanced computerized tomography

CRS:

Cytoreductive surgery

DFS:

Disease-free survival

DSRCT:

Desmoplastic small round cell tumor

FDG:

18 Fluorodeoxyglucose

HIPEC:

Hyperthermic intraperitoneal chemotherapy

OS:

Overall survival

PCI:

Peritoneal carcinomatosis index

PET:

Positron emission tomography

RMS:

Rhabdomyosarcoma

SUVmax:

Maximum standardized uptake value

WAP-RT:

Whole abdominopelvic radiation therapy

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Acknowledgements

We thank the patient’s family for consenting to publish their case details.

Author information

Authors and Affiliations

  1. Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, India

    Mufaddal Kazi

  2. Division of Paediatric Surgical Oncology, Department of Surgical Oncology, Tata Memorial Hospital and Advanced Centre for Training Research and Education in Cancer (ACTREC), Tata Memorial Centre, Ernest Borges Road, Parel, Mumbai, 400012, India

    Sajid S. Qureshi

  3. Homi Bhabha National Institute (HBNI), Mumbai, India

    Sajid S. Qureshi

Authors
  1. Mufaddal Kazi
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  2. Sajid S. Qureshi
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Contributions

Mufaddal Kazi: Designed and wrote the manuscript; performed surgery

Sajid S. Qureshi: Designed and critically reviewed the manuscript; performed surgery

Corresponding author

Correspondence to Sajid S. Qureshi.

Ethics declarations

All procedures followed were in accordance with the ethical standards of the responsible committee (institutional and national). Ethics committee approval was not required for the case report. Consent for publication from the patient was obtained.

Competing Interests

The authors declare no competing interests.

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Kazi, M., Qureshi, S.S. Primary Peritoneal Rhabdomyosarcomatosis in a 2-Year-Old Child Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy — Case Report and Review of Literature. Indian J Surg Oncol 12 (Suppl 2), 322–326 (2021). https://doi.org/10.1007/s13193-021-01351-3

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  • DOI: https://doi.org/10.1007/s13193-021-01351-3

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