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Laparoscopic Ovarian Transposition in Rectal Cancer: More than Just Oncological Outcomes

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Indian Journal of Surgical Oncology Aims and scope Submit manuscript

Abstract

Locally advanced rectal cancer (LARC) is treated with neoadjuvant chemoradiotherapy which down stages tumor and improves complete resection rates thus reducing local recurrences. Pelvic radiotherapy improves oncological outcomes; however, it is associated with ovarian irradiation and premature menopause. This has a consequence to fertility and hormone preservation in young women diagnosed with locally advanced rectal cancer. Laparoscopic ovarian transposition is an established method to preserve ovarian function. This review discusses the technique, indications, and limitations of laparoscopic ovarian transposition in young women requiring pelvic radiotherapy.

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References

  1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-tieulent J, Jemal A (2015) Global Cancer Statistics, 2012. CA Cancer J Clin 65(2):87–108

    Article  Google Scholar 

  2. Center MM, Jemal A, Smith RA, Ward E (2010) Worldwide variations in colorectal cancer. Dis Colon Rectum 53:1099

    Article  Google Scholar 

  3. Orsini RG, Verhoeven RHA, Lemmens VEPP, Van Steenbergen LN, De Hingh IHJT, Nieuwenhuijzen GAP et al (2015) Comparable survival for young rectal cancer patients, despite unfavourable morphology and more advanced-stage disease. Eur J Cancer 51(13):1675–1682

    Article  PubMed  Google Scholar 

  4. You YN, Dozois EJ, Boardman LA, Aakre J, Huebner M, Larson DW (2011) Young-onset rectal cancer: presentation, pattern of care and long-term oncologic outcomes compared to a matched older-onset cohort. Ann Surg Oncol 18(9):2469–2476

    Article  PubMed  Google Scholar 

  5. Schmoll HJ, Van cutsem E, Stein A, Valentini V, Glimelius B, Haustermans K et al (2012) Esmo Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making. Ann Oncol 23(10):2479–2516

    Article  CAS  PubMed  Google Scholar 

  6. Wallace WHB, Thomson AB, Kelsey TW (2003) The radiosensitivity of the human oocyte. Hum Reprod Oxf Engl 18(1):117–121

    Article  CAS  Google Scholar 

  7. Patil PS, Saklani A, Gambhire P, Mehta S, Engineer R, De'Souza A, Chopra S, Bal M (2017) Colorectal cancer in India: An audit from a tertiary center in a low prevalence area. Indian J Surg Oncol 8(4):484–490

  8. Wo JY, Viswanathan AN (2009) Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients. Int J Radiat Oncol Biol Phys 73(5):1304–1312

    Article  PubMed  PubMed Central  Google Scholar 

  9. Gavrilova-Jordan L, Rowe MS, Ballenger CA, Mersereau JE, Hayslip CC (2015) Emergent oocyte cryopreservation with a novel ovarian transposition technique in a colorectal cancer patient: a combined approach for fertility preservation. A Case Report J Reprod Med 60(7–8):354–358

    PubMed  Google Scholar 

  10. Bisharah M, Tulandi T (2003) Laparoscopic preservation of ovarian function: an underused procedure. Am J Obstet Gynecol 188(2):367–370

    Article  PubMed  Google Scholar 

  11. Delotte J, Ferron G, Kuei TLY, Mery E, Gladieff L, Querleu D (2009) Laparoscopic management of an isolated ovarian metastasis on a transposed ovary in a patient treated for stage IB1 adenocarcinoma of the cervix. J Minim Invasive Gynecol 16(1):106–108

    Article  PubMed  Google Scholar 

  12. Barahmeh S, Al Masri M, Badran O, Masarweh M, El-Ghanem M, Jaradat I et al (2013) Ovarian transposition before pelvic irradiation: indications and functional outcome. J Obstet Gynaecol Res 39(11):1533–1537

    Article  PubMed  Google Scholar 

  13. Soda I, Ishiyama H, Ono S, Takenaka K, Arai M, Arai T, Iwase H, Sekiguchi A, Kawakami S, Komori S, Onda T, Hayakawa K (2015) Assessment of transposed ovarian movement: how much of a safety margin should be added during pelvic radiotherapy? J Radiat Res (Tokyo) 56(2):354–359

    Article  Google Scholar 

  14. Morice P, Thiam-Ba R, Castaigne D, Haie-Meder C, Gerbaulet A, Pautier P, Duvillard P, Michel G (1998) Fertility results after ovarian transposition for pelvic malignancies treated by external irradiation or brachytherapy. Hum Reprod Oxf Engl 13(3):660–663

    Article  CAS  Google Scholar 

  15. Morice P, Castaigne D, Haie-Meder C, Pautier P, El Hassan J, Duvillard P et al (1998 Nov) Laparoscopic ovarian transposition for pelvic malignancies: indications and functional outcomes. Fertil Steril 70(5):956–960

    Article  CAS  PubMed  Google Scholar 

  16. Sioulas VD, Jorge S, Chern J-Y, Schiavone MB, Weiser MR, Kelvin JF, Gardner GJ, Sonoda Y, Abu-Rustum NR, Goodman KA, Leitao MM (2017) Robotically assisted laparoscopic ovarian transposition in women with lower gastrointestinal cancer undergoing pelvic radiotherapy. Ann Surg Oncol 24(1):251–256

    Article  PubMed  Google Scholar 

  17. Han S-S, Kim YH, Lee S-H, Kim GJ, Kim HJ, Kim JW, Park NH, Song YS, Kang SB (2011 Jul) Underuse of ovarian transposition in reproductive-aged cancer patients treated by primary or adjuvant pelvic irradiation. J Obstet Gynaecol Res 37(7):825–829

    Article  PubMed  Google Scholar 

  18. Kurt M, Uncu G, Cetintas SK, Kucuk N, Guler S, Ozkan L (2007) Successful spontaneous pregnancy in a patient with rectal carcinoma treated with pelvic radiotherapy and concurrent chemotherapy: the unique role of laparoscopic lateral ovary transposition. Eur J Gynaecol Oncol 28(5):408–410

    CAS  PubMed  Google Scholar 

  19. Köhler C, Marnitz S, Biel P, Cordes T (2016) Successful delivery in a 39-year-old patient with anal Cancer after fertility-preserving surgery followed by primary chemoradiation and low anti-Mullerian hormone level. Oncology 91(5):295–298

    Article  PubMed  Google Scholar 

  20. Morris SN, Ryley D (2011) Fertility preservation: nonsurgical and surgical options. Semin Reprod Med 29(2):147–154

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Gynaecological Oncology, Tata Memorial Centre, Mumbai, India

    T. S. Shylasree

  2. Department of Gastroenterology, Tata Memorial Centre, Mumbai, India

    Prachi Patil

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  1. T. S. Shylasree
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  2. Prachi Patil
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Correspondence to T. S. Shylasree.

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Shylasree, T.S., Patil, P. Laparoscopic Ovarian Transposition in Rectal Cancer: More than Just Oncological Outcomes. Indian J Surg Oncol 10, 309–312 (2019). https://doi.org/10.1007/s13193-019-00872-2

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  • DOI: https://doi.org/10.1007/s13193-019-00872-2

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