Abstract
Gestational trophoblastic disease spectrum ranges from benign hydatidiform mole to trophoblastic malignancy (placental site trophoblastic tumor and choriocarcinoma). Benign gestational trophoblastic disease occurs in women of reproductive age and is extremely rare in postmenopausal women. We describe a case of complete vesicular mole in a 55-year-old postmenopausal woman complaining of postmenopausal bleeding. To our knowledge, our case represents one of the rare descriptions in the world literature of a benign complete hydatidiform mole in a postmenopausal woman.
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References
Garcia M et al (2004) Hydatidiform mole in a postmenopausal woman. Arch Pathol Lab Med 128:1039–1042
Desai NR et al (2010) Choriocarcinoma in a 73-year-old woman: a case report and review of the literature. J Med Case Rep 4:379
Garcia M, Romaguera RL, Gomez-Fernandez C (2004) A hydatidiform mole in a postmenopausal woman. A case report and review of the literature. Arch Pathol Lab Med 128(9):1039–1042
Malkwi H, Baraqawi R, Abu-Kheit S, Hiasat M (2003) Molar pregnancy in a 53 years old patient. JRMS 10(2):58–59
Fisher RA, Newlands ES (1998) Gestational trophoblastic disease molecular and genetic studies. J Reprod Med 43(1):87–97
Castrillon DH, Sun D, Weremowicz S, Fisher RA, Crum CP, Genest DR (2001) Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product p57KIP2. Am J Surg Pathol 25:1225–1230
Al-Bozom IA (2000) P53 and Bcl-2 oncoprotein expression in placentas with hydropic changes and partial and complete moles. APMIS 108:756–760
Tsukamoto N, Iwasaka T, Kashimura Y, Uchino H, Kashimura M, Matsuyama T (1985) Gestational trophoblastic disease in women aged 50 or more. Gynecol Oncol 20:53–61
Davidson SA, Gottesfeld J, La Rosa FG (1997) Molar pregnancy in a 60-year-old woman. Int J Gynecol Obstet 56:53–55
Rabczynski J, Kochman A, Prudlak E, Lewandowski M (2000) Hydatidiform mole in 59-year-old woman: a case report. Ginekol Pol 71:152–154
Jequier A, Winterton WR (1973) Diagnostic problems of trophoblastic disease in women aged 50 or more. Obstet Gynecol 42:378–387
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
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El-Agwany, A.S., Rady, H.A. & Hegab, H.M. Complete Molar Pregnancy in Postmenopausal Woman. Indian J Surg Oncol 8, 185–187 (2017). https://doi.org/10.1007/s13193-016-0603-4
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DOI: https://doi.org/10.1007/s13193-016-0603-4