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Inflammatory Myofibroblastic Tumor of Liver Masquerading as Focal Nodular Hyperplasia in a Patient with Non-Cirrhotic Portal Hypertension and Biliary Pancreatitis

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Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare lesion of undetermined pathogenesis characterized by proliferation of spindled myofibroblast cells in a collagenized inflammatory background. It is usually benign but may show local infiltration or, in rare cases, metastasis. IMT has been observed in almost all solid organs; however, involvement of liver is exceptional. Its symptoms and radiological findings can mimic malignancy and pose diagnostic difficulties. The authors report the case of a 43-year-old woman with non-cirrhotic portal hypertension and gall stone induced acute pancreatitis having a mass in the right lobe of the liver which was initially diagnosed as focal nodular hyperplasia on imaging but proved to be inflammatory myofibroblastic tumor on pathological and immunohistochemical examination. The lesion resolved with conservative management without the need for surgical intervention.

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All authors state that there are no conflicts of interests.

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Authors and Affiliations

  1. Department of Radiology, Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, Off Abdul Gaffar Khan Marg, New Delhi, 110070, India

    Vivek Kasana, S. Rajesh & Udit Chauhan

  2. Department of Pathology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India

    Chhagan Bihari

  3. Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India

    Ashok Choudhury & Shiv K. Sarin

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  1. Vivek Kasana
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  2. S. Rajesh
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  3. Udit Chauhan
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  4. Chhagan Bihari
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  5. Ashok Choudhury
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  6. Shiv K. Sarin
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Correspondence to S. Rajesh.

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Kasana, V., Rajesh, S., Chauhan, U. et al. Inflammatory Myofibroblastic Tumor of Liver Masquerading as Focal Nodular Hyperplasia in a Patient with Non-Cirrhotic Portal Hypertension and Biliary Pancreatitis. Indian J Surg Oncol 7, 110–114 (2016). https://doi.org/10.1007/s13193-015-0381-4

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  • DOI: https://doi.org/10.1007/s13193-015-0381-4

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