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Usefulness of 18F-FDG PET/CT to Detect Metastatic Mucinous Adenocarcinoma Within an Inguinal Hernia

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Abstract

Metastatic mucinous adenocarcinoma in an inguinal hernia is a rare disease and the image findings of 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) are little known. Here, we introduce a 57-year-old man with metastatic mucinous adenocarcinoma in an inguinal hernia. On initial 18F-FDG PET/CT, hypermetabolism was observed in mucinous adenocarcinoma of the cecum, and adenocarcinomas of the transverse and ascending colon, respectively. Follow-up 18F-FDG PET/CT revealed newly developed multiple hypermetabolism in peritoneal seeding masses and nodules in the pelvic cavity and scrotum. Peritoneal carcinomatosis in the right pelvic side wall was extended to the incarcerated peritoneum and mesentery in the right inguinoscrotal hernia.18F-FDG PET/CT was useful to reveal unexpected peritoneal seeding within the inguinal hernia. Also, this case demonstrated that metastatic mucinous adenocarcinomas had variably intense FDG uptake.

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References

  1. Kingsnorth A, LeBlanc K. Hernias: inguinal and incisional. Lancet. 2003;362:1561–71.

    Article  PubMed  Google Scholar 

  2. Page B, Paterson C, Young D, O’Dwyer PJ. Pain from primary inguinal hernia and the effect of repair on pain. Br J Surg. 2002;89:1315–8.

    Article  CAS  PubMed  Google Scholar 

  3. Fitzgibbons RJ, Giobbie-Hurder A, Gibbs JO, et al. Watchful waiting vs repair of inguinal hernia in minimally symptomatic men: a randomized clinical trial. JAMA. 2006;295:285–92.

    Article  CAS  PubMed  Google Scholar 

  4. Wasserberg N, Purim O, Bard V, Kundel Y, Gordon N, Groshar D, et al. Early postoperative F-18-FDG PET/CT in high-risk stage III colorectal cancer. Clin Nucl Med. 2015;40:E222–7.

    Article  PubMed  Google Scholar 

  5. Tural D, Selcukbiricik F, Sager S, Akar E, Yildiz O, Serdengecti S. PET-CT changes the management and improves outcome in patients with recurrent colorectal cancer. J Cancer Res Ther. 2014;10:121–6.

    Article  PubMed  Google Scholar 

  6. Byun BH, Moon SM, Shin US, Lim I, Kim BI, Choi CW, et al. Prognostic value of (18) F-FDG uptake by regional lymph nodes on pretreatment PET/CT in patients with resectable colorectal cancer. Eur J Nucl Med Mol Imaging. 2014;41:2203–11.

    Article  CAS  PubMed  Google Scholar 

  7. Ogawa S, Itabashi M, Kondo C, Momose M, Sakai S, Kameoka S. Prognostic value of total lesion glycolysis measured by F-18-FDG-PET/CT in patients with colorectal cancer. Anticancer Res. 2015;35:3495–500.

    CAS  PubMed  Google Scholar 

  8. Chang JM, Lee HJ, Lee HY, Lee JJ, Chung JK, Im JG. False positive and false negative FDG-PET scans in various thoracic diseases. Korean J Radiol. 2006;7:57–69.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Berger KL, Nicholson SA, Dehdashti F, Siegel BA. FDG PET evaluation of mucinous neoplasms: correlation of FDG uptake with histopathologic features. AJR Am J Roentgenol. 2000;174:1005–8.

    Article  CAS  PubMed  Google Scholar 

  10. Huang S, Sun C, Li X, Guan J, Feng S, Peng Z, et al. Comprehensive application of CT and PET/CT in diagnosing colorectal mucinous and non-mucinous adenocarcinoma. Zhonghua Wei Chang Wai Ke Za Zhi. 2014;17:230–4.

    CAS  PubMed  Google Scholar 

  11. Murakami S, Saito H, Karino F, Kondo T, Oshita F, Ito H, et al. 18F-fluorodeoxyglucose uptake on positron emission tomography in mucinous adenocarcinoma. Eur J Radiol. 2013;82:e721–5.

    Article  PubMed  Google Scholar 

  12. Lee JW, Lee SM, Lee MS, Shin HC. Role of (1)(8)F-FDG PET/CT in the prediction of gastric cancer recurrence after curative surgical resection. Eur J Nucl Med Mol Imaging. 2012;39:1425–34.

    Article  PubMed  Google Scholar 

  13. Nicholson CP, Donohue JH, Thompson GB, Lewis JE. A study of metastatic cancer found during inguinal hernia repair. Cancer. 1992;69:3008–11.

    Article  CAS  PubMed  Google Scholar 

  14. Matsumoto G, Ise H, Inoue H, Ogawa H, Suzuki N, Matsuno S. Metastatic colon carcinoma found within an inguinal hernia sac: report of a case. Surg Today. 2000;30:74–7.

    Article  CAS  PubMed  Google Scholar 

  15. Chung SD, Yu HJ, Lin WC, Huang KH. Metastatic prostatic adenocarcinoma in an inguinal hernia sac in a patient with undetectable serum prostate specific antigen level. J Formos Med Assoc. 2007;106:397–9.

    Article  PubMed  Google Scholar 

  16. Liu P-H, Kung W-C, Wu Y-C, Chien S-T, Chang W-Y, Hsu C-W. Metastatic malignant gastrointestinal stromal tumor mimicking a right incarcerated inguinal hernia. Formos J Surg. 2014;47:189–92.

    Article  Google Scholar 

  17. Marsden M, Curtis N, McGee S, Bracey E, Branag G, Sleighta S. Intrasaccular caecal adenocarcinoma presenting as enlarging right inguinoscrotal hernia. Int J Surg Case Rep. 2014;5.

  18. Langner C, Harbaum L, Pollheimer MJ, Kornprat P, Lindtner RA, Schlemmer A, et al. Mucinous differentiation in colorectal cancer—indicator of poor prognosis? Histopathology. 2012;60:1060–72.

    Article  PubMed  Google Scholar 

  19. Bosman FT, World Health Organization, International Agency for Research on Cancer. WHO classification of tumours of the digestive system. 4th ed. World Health Organization classification of tumours, vol 3. International Agency for Research on Cancer: Lyon; 2010.

    Google Scholar 

  20. Foda AAM, El-Hawary AK, Aziz AA. Colorectal adenocarcinoma with mucinous component: relation of MMP-13, EGFR, and E-cadherin expressions to clinicopathological features and prognosis. APMIS. 2015;123:502–8.

    Article  CAS  PubMed  Google Scholar 

  21. Nitsche U, Zimmermann A, Spath C, Muller T, Maak M, Schuster T, et al. Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis. Ann Surg. 2013;258:775–82. discussion 82–3.

    Article  PubMed Central  PubMed  Google Scholar 

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Correspondence to Byung Wook Min or Jae Seon Eo.

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Conflict of Interest

Hyo Jung Seo, Jae Seon Eo, Byung Wook Min, Sun Il Lee, Sang Hee Kang, Sung Yup Jung, Sang Chul Oh and Jae Gol Choe declare that they have no conflict of interest.

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All procedures performed in this study involving human participant were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

The patient gave his informed consent prior to his inclusion in the study.

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Seo, H.J., Min, B.W., Eo, J.S. et al. Usefulness of 18F-FDG PET/CT to Detect Metastatic Mucinous Adenocarcinoma Within an Inguinal Hernia. Nucl Med Mol Imaging 50, 85–89 (2016). https://doi.org/10.1007/s13139-015-0379-4

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  • DOI: https://doi.org/10.1007/s13139-015-0379-4

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