Abstract
Cognitive behavioral group therapy (CBGT) has been reported to be more effective than a mindfulness-based stress reduction program (MBSR) in reducing symptoms of social anxiety disorder (SAD). The present study determined whether CBGT and MBSR differentially affected subjective anxiety and physiological response to a stressful speaking task. The sample comprised 38 medication-free SAD patients who participated in a previously published trial comparing CBGT and MBSR; an additional 30 participants were healthy control (HC) volunteers. Patients performed a speech task before and after treatment while HC performed it only once. Subjective anxiety and core symptoms of SAD were assessed with visual analog scales (VAS), and physiological responses included salivary cortisol and heart rate variability. Prior to treatment, the speech task induced greater increases in anxiety and SAD symptoms in patients compared to HC. After treatment, VAS ratings during the task decreased in both treatment groups. The most significant improvement overall was observed with CBGT, with their responses being comparable to that of HC. No physiological differences were found as a function of treatment. Although CBGT produced the best results, MBSR was nonetheless associated with a significant decrease in subjective anxiety and symptoms of SAD during the speech task.
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References
Acarturk, C., Smit, F., de Graaf, R., van Straten, A., ten Have, M., & Cuijpers, P. (2009). Economic costs of social phobia: a population-based study. Journal of Affective Disorders, 115(3), 421–429. doi:10.1016/j.jad.2008.10.008.
Aderka, I. M. (2009). Factors affecting treatment efficacy in social phobia: the use of video feedback and individual vs. group formats. Journal of Anxiety Disorders, 23(1), 12–17. doi:10.1016/j.janxdis.2008.05.003.
Allen, A. P., Kennedy, P. J., Cryan, J. F., Dinan, T. G., & Clarke, G. (2014). Biological and psychological markers of stress in humans: focus on the trier social stress test. Neuroscience and Biobehavioral Reviews, 38, 94–124. doi:10.1016/j.neubiorev.2013.11.005.
American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders (4th Ed.- Text Revision).Xxvii, 943 Pp. Arlington, VA, US: American Psychiatric Publishing, Inc.; US.
Arch, J. J., & Craske, M. G. (2010). Laboratory stressors in clinically anxious and non-anxious individuals: the moderating role of mindfulness. Behaviour Research and Therapy, 48(6), 495–505. doi:10.1016/j.brat.2010.02.005.
Baer, R. A. (2003). Mindfulness training as a clinical intervention: a conceptual and empirical review. Clinical Psychology: Science and Practice, 10(2), 125–143.
Bogels, S. M., Sijbers, G. F. V. M., & Voncken, M. (2006). Mindfulness and task concentration training for social phobia: a pilot study. Journal of Cognitive Psychotherapy, 20(1), 33–44.
Brewer, J. A., Sinha, R., Chen, J. A., Michalsen, R. N., Babuscio, T. A., Nich, C., . . . Rounsaville, B. J. (2009). Mindfulness training and stress reactivity in substance abuse: Results from a randomized, controlled stage I pilot study. Substance Abuse: Official Publication of the Association for Medical Education and Research in Substance Abuse, 30(4), 306–317. doi:10.1080/08897070903250241.
Burg, J. M., Wolf, O. T., & Michalak, J. (2012). Mindfulness as self-regulated attention: associations with heart rate variability. Swiss Journal of Psychology/Schweizerische Zeitschrift Fur Psychologie/Revue Suisse De Psychologie, 71(3), 135–139.
Buske-Kirschbaum, A., Geiben, A., Hollig, H., Morschhauser, E., & Hellhammer, D. (2002). Altered responsiveness of the hypothalamus-pituitary-adrenal axis and the sympathetic adrenomedullary system to stress in patients with atopic dermatitis. The Journal of Clinical Endocrinology and Metabolism, 87(9), 4245–4251.
Butler, A. C., Chapman, J. E., Forman, E. M., & Beck, A. T. (2006). The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clinical Psychology Review, 26(1), 17–31. doi:10.1016/j.cpr.2005.07.003.
Clark, D. M., & McManus, F. (2002). Information processing in social phobia. Biological Psychiatry, 51(1), 92–100.
Craske, M. G., Niles, A., Burklund, L., Wolitzky-Taylor, K., Vilardaga, J., Arch, J., … Lieberman, M. (2014). Randomized control trial of cognitive behavioral therapy and acceptance and commitment therapy for social phobia: Outcomes and moderators. Journal of Counsulting and Clinical Psychology, 82(6), 1034–1048.
Elzinga, B. M., Spinhoven, P., Berretty, E., de Jong, P., & Roelofs, K. (2010). The role of childhood abuse in HPA-axis reactivity in social anxiety disorder: a pilot study. Biological Psychology, 83(1), 6. doi:10.1016/j.biopsycho.2009.09.006.
Fiocco, J. F., Joober, R., & Lupien, S. J. (2007). Education modulates cortisol reactivity to the Trier Social Stress Test in middle-aged adults. Psychoneuroendocinology, 32(8–10), 1158–1163.
Fjorback, L. O., Arendt, M., Ornbol, E., Fink, P., & Walach, H. (2011). Mindfulness-based stress reduction and mindfulness-based cognitive therapy: a systematic review of randomized controlled trials. Acta Psychiatrica Scandinavica, 124(2), 102–119. doi:10.1111/j.1600-0447.2011.01704.x.
Friedman, B. H. (2007). An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone. Biological Psychology, 74(2), 185–199. doi:10.1016/j.biopsycho.2005.08.009.
Gerlach, A. L., Wilhelm, F. H., & Roth, W. T. (2003). Embarrassment and social phobia: the role of parasympathetic activation. Journal of Anxiety Disorders, 17(2), 197–210.
Gerra, G., Zaimovic, A., Mascetti, G. G., Gardini, S., Zambelli, U., Timpano, M., … Brambilla, F. (2001). Neuroendocrine responses to experimentally-induced psychological stress in healthy humans. Psychoneuroendocrinology, 26(1), 91–107.
Goldin, P., Ziv, M., Jazaieri, H., Hahn, K., & Gross, J. J. (2013). MBSR vs aerobic exercise in social anxiety: FMRI of emotion regulation of negative self-beliefs. Social Cognitive and Affective Neuroscience, 8(1), 65–72. doi:10.1093/scan/nss054.
Grossman, P., Wilhelm, F. H., Kawachi, I., & Sparrow, D. (2001). Gender differences in psychophysiological responses to speech stress among older social phobics: Congruence and incongruence between self-evaluative and cardiovascular reactions. Psychosomatic Medicine, 63(5), 765–777.
Heimberg, R. G., & Becker, R. E. (2002). Cognitive–behavioral group therapy for social phobia: basic mechanisms and clinical strategies. New York: The Guildford Press.
Hofmann, S. G., & Bogels, S. M. (2006). Recent advances in the treatment of social phobia: introduction to the special issue. Journal of Cognitive Psychotherapy, 20(1), 3–5.
Hofmann, S. G., & Smits, J. A. (2008). Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials. The Journal of Clinical Psychiatry, 69(4), 621–632.
Kabat-Zinn, J. (1990). Full catastrophe living: using the wisdom of the body and the mind to fase stress, pain and illness. New York: Dell.
Kabat-Zinn, J. (2003). Mindfulness-based interventions in context: past, present, and future. Clinical Psychology: Science and Practice, 10(2), 144–156.
Kabat-Zinn, J., & Santorelli, S. (1993). Mindfulness-based stress reduction professional training resource manual.
Kaviani, H., Javaheri, F., & Hatami, N. (2011). Mindfulness-based cognitive therapy (MBCT) reduces depression and anxiety induced by real stressful setting in non-clinical population. International Journal of Psychology & Psychological Therapy, 11(2), 285–296.
Kirschbaum, C., & Hellhammer, D. H. (1994). Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology, 19(4), 313–333.
Kirschbaum, C., Prussner, J. C., Stone, A. A., Federenko, I., Gaab, J., Lintz, D., & Hellhammer, D. H. (1995). Persistent high cortisol responses to repeated psychological stress in a subpopulation of healthy men. Psychosomatic Medicine, 57(5), 468–474.
Kirschbaum, C., Kudielka, B. M., Gaab, J., Schommer, N. C., & Hellhammer, D. H. (1999). Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosomatic Medicine, 61, 154–162.
Klatt, M. D., Buckworth, J., & Malarkey, W. B. (2009). Effects of low-dose mindfulness-based stress reduction (MBSR-ld) on working adults. Health Education & Behavior: The Official Publication of the Society for Public Health Education, 36(3), 601–614. doi:10.1177/1090198108317627.
Kocovski, N. L., Fleming, J. E., & Rector, N. A. (2009). Mindfulness and acceptance-based group therapy for social anxiety disorder: an open trial. Cognitive and Behavioral Practice, 16(3), 276–289.
Kocovski, N. L., Fleming, J. E., Hawley, L. L., Huta, V., & Antony, M. M. (2013). Mindfulness and acceptance-based group therapy versus traditional cognitive behavioral group therapy for social anxiety disorder: a randomized controlled trial. Behaviour Research and Therapy, 51, 889–898.
Koszycki, D., Benger, M., Shlik, J., & Bradwejn, J. (2007). Randomized trial of a meditation-based stress reduction program and cognitive behavior therapy in generalized social anxiety disorder. Behaviour Research and Therapy, 45(10), 2518–2526. doi:10.1016/j.brat.2007.04.011.
Kudielka, B. N., Gierens, A., Hellhammer, D. H., Wüst, S., & Schlotz, W. (2012). Salivary cortisol in ambulatory assessment—some dos and don’ts and some open questions. Psychosomatic Medicine, 74, 418–431.
Leahy, R. L., & Holland, S. J. (2000). Treatment plans and interventions for depression and anxiety disorders. New York: Guilford Press.
Libby, D. J., Worhunsky, P. D., Pilver, C. E., & Brewer, J. A. (2012). Meditation-induced changes in high-frequency heart rate variability predict smoking outcomes. Frontiers in Human Neuroscience, 6, 54. doi:10.3389/fnhum.2012.00054.
Manzaneque, J. M., Vera, F. M., Ramos, N. S., Godoy, Y. A., Rodriguez, F. … Enguix, A. (2011). Psychobiological modulation in anxious and depressed patients after a mindfulness meditation programme: a pilot study. Stress and Health: Journal of the International Society for the Investigation of Stress, 27(3), 216–222.
Marcus, M. T., Fine, M., Moeller, F. G., Khan, M. M., Pitts, K., Swank, P. R., & Liehr, P. (2003). Change in stress levels following mindfulness-based stress reduction in a therapeutic community. Addictive Disorders & Their Treatment, 2(3), 63–68.
Martinez, J. M., Garakani, A., Kaufmann, H., Aaronson, C. J., & Gorman, J. M. (2010). Heart rate and blood pressure changes during autonomic nervous system challenge in panic disorder patients. Psychosomatic Medicine, 72(5), 442–449. doi:10.1097/PSY.0b013e3181d972c2.
Mauss, I. B., Wilhelm, F. H., & Gross, J. J. (2003). Autonomic recovery and habituation in social anxiety. Psychophysiology, 40(4), 648–653.
Mauss, I. B., Wilhelm, F. H., & Gross, J. J. (2004). Is there less to social anxiety than meets the eye? emotion experience, expression, and bodily responding. Cognition and Emotion, 18(5), 631–662. doi:10.1080/02699930341000112.
Payne, L. A., Hibel, L. C., Granger, D. A., Tsao, J. C., & Zelter, L. K. (2014). Relationship of salivary alpha amylase and cortisol to social anxiety in healthy children undergoing laboratory pain tasks. Journal of Child and Adolescent Behaviour, 2, 1–12. doi:10.4172/jcalb.1000129.
Piet, J., Hougaard, E., Hecksher, M. S., & Rosenberg, N. K. (2010). A randomized pilot study of mindfulness-based cognitive therapy and group cognitive-behavioral therapy for young adults with social phobia. Scandinavian Journal of Psychology. doi:10.1111/j.1467-9450.2009.00801.x.
Ponniah, K., & Hollon, S. D. (2008). Empirically supported psychological interventions for social phobia in adults: a qualitative review of randomized controlled trials. Psychological Medicine, 38(1), 3–14. doi:10.1017/S0033291707000918.
Porges, S. W., Doussard-Roosevelt, J. A., & Maiti, A. J. (1994). Vagal tone and the physiological regulation of emotion. In N. A. Fox (Ed.), The development of emotion regulation. Chicago: University of Chicago Press.
Pruessner, J. C., Kirschbaum, C., Meinlschmid, G., & Hellhammer, D. H. (2003). Two formulas for computation of the area under the curve represent measures of total concentration versus time-dependent change. Psychoneuroendocrinology, 28(7), 916–931.
Roelofs, K., van Peer, J., Berretty, E., Jong, P., Spinhoven, P., & Elzinga, B. M. (2009). Hypothalamus-pituitary-adrenal axis hyperresponsiveness is associated with increased social avoidance behavior in social phobia. Biological Psychiatry, 65(4), 336–343. doi:10.1016/j.biopsych.2008.08.022.
Roemer, L., & Orsillo, S. M. (2003). Mindfulness: a promising intervention strategy in need of further study. Clinical Psychology: Science and Practice, 10(2), 172–178.
Stein, M. B., & Asmundson, G. J. (1994). Autonomic function in panic disorder: cardiorespiratory and plasma catecholamine responsivity to multiple challenges of the autonomic nervous system. Biological Psychiatry, 36(8), 548–558.
Stein, M. B., & Stein, D. J. (2008). Social anxiety disorder. Lancet, 371(9618), 1115–1125. doi:10.1016/S0140-6736(08)60488-2.
Stratford, T., Meara, A., & Lal, S. (2014). Heart rate variability and the anxious client: cardiac autonomic and behavioral associations with therapeutic alliance. Journal of Nervous and Mental Disease, 202(8), 613–619.
Tabachnick, B. G., & Fidell, L. S. (2007). Experimental design using ANOVA. US: Duxbury.
van Veen, J. F., van Vliet, I. M., Derijk, R. H., van Pelt, J., Mertens, B., & Zitman, F. G. (2008). Elevated alpha-amylase but not cortisol in generalized social anxiety disorder. Psychoneuroendocrinology, 33(10), 1313–1321. doi:10.1016/j.psyneuen.2008.07.004.
Wewers, M. E., & Lowe, N. K. (1990). A critical review of visual analogue scales in the measurement of clinical phenomena. Research in Nursing & Health, 13(4), 227–236.
Williams, V. S., Morlock, R. J., & Feltner, D. (2010). Psychometric evaluation of a visual analog scale for the assessment of anxiety. Health and Quality of Life Outcomes, 8, 57-7525-8-57. doi:10.1186/1477-7525-8-57.
Witek-Janusek, L., Albuquerque, K., Chroniak, K. R., Chroniak, C., Durazo-Arvizu, R., & Mathews, H. L. (2008). Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain, Behavior, and Immunity, 22(6), 969–981. doi:10.1016/j.bbi.2008.01.012.
Acknowledgments
This research was supported in part by the University of Ottawa Medical Research Fund. We would like to thank Melodie Benger who conducted the MBSR group and Maria Pizzi, Murray Weeks, and Emilie Chan for research assistance. We also would like to acknowledge Dr. Shlik.
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Faucher, J., Koszycki, D., Bradwejn, J. et al. Effects of CBT Versus MBSR Treatment on Social Stress Reactions in Social Anxiety Disorder. Mindfulness 7, 514–526 (2016). https://doi.org/10.1007/s12671-015-0486-4
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DOI: https://doi.org/10.1007/s12671-015-0486-4