Abstract
A combined analysis of pregnancy-associated plasma protein-A (PAPP-A) values, human chorionic gonadotropin, and pulsation index of the uterine arteries was performed as part of a first trimester and serum content of eight regulatory autoantibodies screening. It was found that including autoantibodies to insulin, PAPP-A, and collagen into the analysis significantly improved the sensitivity and specificity of the prognosis and could be employed to form an intrauterine growth restriction (IUGR) risk group.
Similar content being viewed by others
References
Goetzinger, K. R., Singla, A., Gerkowicz, S., et al. (2009). The efficiency of first-trimester serum analytes and maternal characteristics in predicting fetal growth disorders. American Journal of Obstetrics and Gynecology, 201(4), 412–416.
Savelyeva, G.M., Bugerenko, E.Y., Panin, O.B. (2013) Prognostic significance of violations of utero-placental circulation in the I trimester of pregnancy in patients with a history of obstetric history. Bulletin of Medical Sciences. - 2013. - № 7. - S. 4-8.2. -T. 10. - P. 62-67.
Dugoff, L., Lynch, A. M., Cioffi-Ragan, D., et al. (2005). First trimester uterine artery Doppler abnormalities predict subsequent intrauterine growth restriction. American Journal of Obstetrics and Gynecology, 193(3), 1208–1212.
Poon, L. C., Stratieva, V., Piras, S., et al. (2010). Hypertensive disorders in pregnancy: combined screening by uterine artery Doppler, blood pressure and serum PAPP-A at 11-13 weeks. Prenatal Diagnosis, 30(3), 216–223.
Poletaev, A., & Osipenko, L. (2009). General network of natural autoantibodies as immunological homunculus (Immunculus). Autoimmunity Review, 2(5), 264–271.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Zamaleeva, R.S., Cherepanova, N.A., Frizin, D.V. et al. The Possibilities Given by First Trimester Prenatal Screening Data, Uterine Arteries Pulsation Index, and Regulatory Autoantibodies in Predicting Intrauterine Growth Restriction in Females. BioNanoSci. 7, 360–362 (2017). https://doi.org/10.1007/s12668-016-0367-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12668-016-0367-x