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Evaluation of the impact of celiac disease and its dietary manipulation on children and their caregivers

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Indian Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

Background

Lifelong dietary abstinence of gluten is the only treatment available for celiac disease. This is not only challenging but also leads to several psychosocial morbidities and affects the quality of life of children and their parents.

Methods

An observational study was conducted on 50 children (5–18 years) diagnosed with celiac disease on gluten-free diet for at least 6 months and their parents to evaluate of the impact of celiac disease and its dietary manipulation on them. The quality of life was assessed by applying celiac disease-specific questionnaire. Dietary compliant and noncompliant groups were compared to assess the factors leading to poor compliance. Anthropometric parameters were utilized to ascertain clinical response.

Results

Fifty children with a mean age of 9.06 years were enrolled. Seventy-four percent of the children were compliant. In the compliant group, height and weight correlated with dietary compliance (p = 0.0087 and p = 0.023). Dietary compliance was found to be better in adolescent males and single child and those living in nuclear families. Quality of life was found to be higher among parents of noncompliant children (quality of life score: 63) as compared to the compliant children (quality of life score: 59). The acceptance of celiac disease was better among children whose parents had a higher level of education. The scale diet proved to be a useful indicator for evaluating compliance among children (p = 0.0036).

Conclusions

Noncompliance to gluten-free diet was noted in 24 % of children with celiac disease.

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Conflict of interest

BK, AL, SK, MB, KR, and SK declare that they have no conflict of interest.

Ethical approval

All procedures performed in this study involving human participants were in accordance with the ethical standards of the Ethic Committee of the South Ural State Medical University and with the 1964 Helsinki declaration and its later amendments. All patients gave written informed consent for participation in the study.

Funding

BK received a short-term studentship from ICMR.

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Authors and Affiliations

  1. Division of Genetics, Department of Pediatrics, Maulana Azad Medical College, Associated Lok Nayak Hospital, Bahadur Shah Zafar Marg, New Delhi, 110 002, India

    Bisman Khurana, Avinash Lomash, Sumaira Khalil, K. Rajeshwari & Seema Kapoor

  2. Department of Pediatrics, Kailash Hospital, Sector 27, Noida, 201 301, India

    Malvika Bhattacharya

Authors
  1. Bisman Khurana
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  2. Avinash Lomash
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  3. Sumaira Khalil
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  4. Malvika Bhattacharya
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  5. K. Rajeshwari
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  6. Seema Kapoor
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Corresponding author

Correspondence to Seema Kapoor.

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Khurana, B., Lomash, A., Khalil, S. et al. Evaluation of the impact of celiac disease and its dietary manipulation on children and their caregivers. Indian J Gastroenterol 34, 112–116 (2015). https://doi.org/10.1007/s12664-015-0563-6

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  • DOI: https://doi.org/10.1007/s12664-015-0563-6

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