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Preemptive Oral Ketorolac with Local Tramadol Versus Oral Ketorolac in Third Molar Surgery: A Comparative Clinical Trial

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Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Aims

To assess preemptive analgesic efficacy of oral ketorolac with submucous placebo versus oral ketorolac with submucous tramadol during impacted mandibular third molar surgery.

Methodology

A double-blind, split-mouth clinical study was carried on 40 patients having bilateral impacted mandibular third molars. They were divided as group A comprising of 40 patients in whom oral ketorolac with submucous tramadol was administered and group B comprising of 40 patients in whom oral ketorolac with submucous placebo was administered. The study parameters included were pain intensity scores, duration to take 1st rescue analgesia, need of analgesic intake during the first 24 h postoperatively and patient’s experience.

Results

The patient’s experience was found to be better in the group A as compared to group B while evaluating mean pain intensity scores (VRS, VAS); need of postoperative analgesics and drug-related complications.

Conclusion

Preemptive oral ketorolac with tramadol in comparison to oral ketorolac results in better pain relief, longer pain free intervals with minimum rescue analgesics requirement & lesser postoperative analgesics consumption.

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Funding

Self funded.

Author information

Authors and Affiliations

  1. Department of Oral & Maxillofacial Surgery, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India

    Heena Mazhar & Prashant Tamgadge

  2. Oral Medicine & Radiology, EJHS Wellness Center, Adilabad, Telangana, India

    Ratna Samudrawar

  3. Department of Oral Medicine and Radiology, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Wadhamna Road, Hingna, Nagpur, Maharashtra, India

    Rashmi Wasekar

  4. Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, India

    Rahul Vinay Chandra Tiwari

  5. CHC Makdi, Kondagaon, Chhattisgarh, India

    Heena Tiwari

Authors
  1. Heena Mazhar
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  2. Ratna Samudrawar
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  3. Prashant Tamgadge
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  4. Rashmi Wasekar
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  5. Rahul Vinay Chandra Tiwari
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  6. Heena Tiwari
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Correspondence to Heena Mazhar.

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Mazhar, H., Samudrawar, R., Tamgadge, P. et al. Preemptive Oral Ketorolac with Local Tramadol Versus Oral Ketorolac in Third Molar Surgery: A Comparative Clinical Trial. J. Maxillofac. Oral Surg. 21, 227–234 (2022). https://doi.org/10.1007/s12663-020-01400-4

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  • DOI: https://doi.org/10.1007/s12663-020-01400-4

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