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An automatic lung nodule detection and classification using an optimized convolutional neural network and enhanced k-means clustering

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Abstract

Lung cancer can be lethal if it is not found in the initial phases. Lung cancer, nevertheless, is challenging to identify early due to the dimensions and form of the nodules. Imaging specialists require the assistance of automated instruments for accurate interpretation. Therefore, in this paper, automatic lung nodule classification is proposed. In the proposed methodology, there are four phases, namely pre-processing, segmentation, classification, and severity analysis. As a first step, lung nodule images are collected from the dataset and pre-processed. After pre-processing, segmentation is carried out. For segmentation enhanced k-means clustering algorithm is applied. To identify the object as cancerous or benign, the segmented region is then fed into an optimized convolution neural network (OCNN). Here, adaptive sunflower optimization (ASFO) algorithm is used to pick the hyperparameters effectively to improve the effectiveness of the CNN classifier. Finally, from the segmented region, the severity of the patient is evaluated. The efficiency of the presented technique is analyzed based on various metrics and research work compared with different state-of-art-works.

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References

  • Amorim PH, de Moraes TF, da Silva JV, Pedrini H (2019). Lung nodule segmentation based on convolutional neural networks using multi-orientation and patchwise mechanisms. In: VipIMAGE 2019: proceedings of the VII ECCOMAS thematic conference on computational vision and medical image processing, October 16–18, 2019, Porto, Portugal. Springer International Publishing, pp 286–295

  • Aresta G, Jacobs C, Araújo T, Cunha A, Ramos I, van Ginneken B, Campilho A (2019) iW-Net: an automatic and minimalistic interactive lung nodule segmentation deep network. Sci Rep 9(1):1–9

    Article  Google Scholar 

  • Boykov Y, Kolmogorov V (2004) An experimental comparison of mincut/max-flow algorithms for energy minimization in vision. IEEE Trans Pattern Anal Mach Intell 26(9):1124–1137

    Article  Google Scholar 

  • Cavalcanti PG, Shirani S, Scharcanski J, Fong C, Meng J, Castelli J, Koff D (2016) Lung nodule segmentation in chest computed tomography using a novel background estimation method. Quant Imaging Med Surg 6(1):16

    Google Scholar 

  • Chan TF, Vese LA (2001) Active contours without edges. IEEE Trans Image Process 10(2):266–277

    Article  Google Scholar 

  • Chen Q, Xie W, Zhou P, Zheng C, Wu D (2021) Multi-crop convolutional neural networks for fast lung nodule segmentation. IEEE Trans Emerg Top Comput Intell 6(5):1190–1200

    Article  Google Scholar 

  • Dong X, Xu S, Liu Y, Wang A, Saripan MI, Li L, Zhang X, Lu L (2020) Multi-view secondary input collaborative deep learning for lung nodule 3D segmentation. Cancer Imaging 20:1–13

    Article  Google Scholar 

  • El-Regaily SA, Salem MAM, Aziz MHA, Roushdy MI (2017) Lung nodule segmentation and detection in computed tomography. In: 2017 Eighth international conference on intelligent computing and information systems (ICICIS), December. IEEE, pp 72–78

  • Halder A, Chatterjee S, Dey D, Kole S, Munshi S (2020) An adaptive morphology based segmentation technique for lung nodule detection in thoracic CT image. Comput Methods Programs Biomed 197:105720

    Article  Google Scholar 

  • Hesamian MH, Jia W, He X, Wang Q, Kennedy PJ (2021) Synthetic CT images for semi-sequential detection and segmentation of lung nodules. Appl Intell 51:1616–1628

    Article  Google Scholar 

  • Jain S, Indora S, Atal DK (2021) Lung nodule segmentation using salp shuffled shepherd optimization algorithm-based generative adversarial network. Comput Biol Med 137:104811

    Article  Google Scholar 

  • Keetha NV, Annavarapu CSR (2020) U-Det: a modified U-Net architecture with bidirectional feature network for lung nodule segmentation. arXiv preprint arXiv:2003.09293

  • Kido S, Kidera S, Hirano Y, Mabu S, Kamiya T, Tanaka N, Suzuki Y, Yanagawa M, Tomiyama N (2022) Segmentation of lung nodules on CT images using a nested three-dimensional fully connected convolutional network. Fronti Artif Intell 5:782225

    Article  Google Scholar 

  • Kuruvilla J, Gunavathi K (2014) Lung cancer classification using neural networks for CT images. Comput Methods Programs Biomed 113(1):202–209

    Article  Google Scholar 

  • Liu H, Cao H, Song E, Ma G, Xu X, Jin R, Jin Y, Hung CC (2019) A cascaded dual-pathway residual network for lung nodule segmentation in CT images. Physica Med 63:112–121

    Article  Google Scholar 

  • Madero Orozco H, Vergara Villegas OO, Cruz Sánchez VG, Ochoa Domínguez HDJ, Nandayapa Alfaro MDJ (2015) Automated system for lung nodules classification based on wavelet feature descriptor and support vector machine. Biomed Eng Online 14(1):1–20

    Article  Google Scholar 

  • Meraj T, Rauf HT, Zahoor S, Hassan A, Lali MI, Ali L, Bukhari SAC, Shoaib U (2021) Lung nodules detection using semantic segmentation and classification with optimal features. Neural Comput Appl 33:10737–10750

    Article  Google Scholar 

  • Nam CM, Kim J, Lee KJ (2018) Lung nodule segmentation with convolutional neural network trained by simple diameter information. In: 1st Conference on medical imaging with deep learning (MIDL 2018), Amsterdam, The Netherlands

  • Ronneberger O, Fischer P, Brox T (2015) U-net: convolutional networks for biomedical image segmentation. In: Navab N, Hornegger J, Wells WM, Frangi AF (eds) Medical image computing and computer-assisted intervention—MICCAI 2015. Springer International Publishing, Cham, pp 234–241

    Google Scholar 

  • Shen S, Bui AA, Cong J, Hsu W (2015) An automated lung segmentation approach using bidirectional chain codes to improve nodule detection accuracy. Comput Biol Med 57:139–149

    Article  Google Scholar 

  • Singadkar G, Mahajan A, Thakur M, Talbar S (2020) Deep deconvolutional residual network based automatic lung nodule segmentation. J Digit Imaging 33:678–684

    Article  Google Scholar 

  • Song J, Huang SC, Kelly B, Liao G, Shi J, Wu N, Li W, Liu Z, Cui L, Lungre MP, Moseley ME (2021) Automatic Lung Nodule Segmentation and Intra-Nodular Heterogeneity Image Generation. IEEE J Biomed Health Inform 26(6):2570–2581

    Article  Google Scholar 

  • Suji RJ, Bhadouria SS, Dhar J, Godfrey WW (2020) Optical flow methods for lung nodule segmentation on LIDC-IDRI images. J Digit Imaging 33:1306–1324

    Article  Google Scholar 

  • Tyagi S, Talbar SN (2022) CSE-GAN: a 3D conditional generative adversarial network with concurrent squeeze-and-excitation blocks for lung nodule segmentation. Comput Biol Med 147:105781

    Article  Google Scholar 

  • Usman M, Shin YG (2023) DEHA-Net: a dual-encoder-based hard attention network with an adaptive ROI mechanism for lung nodule segmentation. Sensors 23(4):1989

    Article  Google Scholar 

  • Veronica BK (2020) An effective neural network model for lung nodule detection in CT images with optimal fuzzy model. Multimedia Tools Appl 79(19):14291–14311

    Article  Google Scholar 

  • Vijh S, Gaur D, Kumar S (2020) An intelligent lung tumor diagnosis system using whale optimization algorithm and support vector machine. Int J Syst Assur Eng Manag 11(2):374–384

    Article  Google Scholar 

  • Wang S, Zhou M, Liu Z, Liu Z, Gu D, Zang Y, Dong D, Gevaert O, Tian J (2017) Central focused convolutional neural networks: developing a data-driven model for lung nodule segmentation. Med Image Anal 40:172–183

    Article  Google Scholar 

  • Wang S, Jiang A, Li X, Qiu Y, Li M, Li F (2022) DPBET: a dual-path lung nodules segmentation model based on boundary enhancement and hybrid transformer. Comput Biol Med 151:106330

    Article  Google Scholar 

  • Weikert T, Akinci D’Antonoli T, Bremerich J, Stieltjes B, Sommer G, Sauter AW (2019) Evaluation of an AI-powered lung nodule algorithm for detection and 3D segmentation of primary lung tumors. Contrast Media Mol Imaging 2019:1

    Article  Google Scholar 

  • Wu Z, Zhou Q, Wang F (2021) Coarse-to-fine lung nodule segmentation in CT images with image enhancement and dual-branch network. IEEE Access 9:7255–7262

    Article  Google Scholar 

  • Yan X, Pang J, Qi H, Zhu Y, Bai C, Geng X, et al. (2016) Classification of lung nodule malignancy risk on computed tomography images using convolutional neural network: a comparison between 2D and 3D strategies. In: Asian conference on computer vision, November. Springer, Cham, pp 91–101

  • Zhang N, Lin J, Hui B, Qiao B, Yang W, Shang R, Wang X, Lei J (2022) Lung nodule segmentation and recognition algorithm based on multiposition U-net. Comput Math Methods Med 2022:1–11

    Google Scholar 

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Correspondence to M. Dhasny Lydia.

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Lydia, M.D., Prakash, M. An automatic lung nodule detection and classification using an optimized convolutional neural network and enhanced k-means clustering. J Ambient Intell Human Comput 14, 16973–16984 (2023). https://doi.org/10.1007/s12652-023-04711-9

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