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One-Pot, Three-Component Synthesis of 2,3-Dihydro-4(1H)-Quinazolinones Catalyzed by Perchlorated Zirconia (HClO4/ZrO2) Nanoparticles as a Solid Acid Catalyst

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Abstract

Mono and disubstituted 2,3-dihydroquinazolin-4(1H)-ones were obtained in good yields via a one-pot, three component reaction of isatoic anhydride and aromatic aldehydes with ammonium acetate or primary amines in the presence of perchlorated zirconia (HClO4/ZrO2) nano particles as an efficient solid acid catalyst under solvent-free conditions. Simple workup and reusability of the catalyst are advantages of this method.

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Acknowledgments

We are thankful to the Yazd University Research Council for partial support of this work.

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Authors and Affiliations

  1. Department of Chemistry, Yazd University, Yazd, Iran

    Zeinab Hamidi & Mohammad Abdollahi-Alibeik

  2. Materials Engineering Department, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, Iran

    Seyed Yousef Mosavian

Authors
  1. Zeinab Hamidi
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  2. Mohammad Abdollahi-Alibeik
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  3. Seyed Yousef Mosavian
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Correspondence to Zeinab Hamidi.

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Hamidi, Z., Abdollahi-Alibeik, M. & Mosavian, S. One-Pot, Three-Component Synthesis of 2,3-Dihydro-4(1H)-Quinazolinones Catalyzed by Perchlorated Zirconia (HClO4/ZrO2) Nanoparticles as a Solid Acid Catalyst. Silicon 10, 2491–2497 (2018). https://doi.org/10.1007/s12633-018-9781-8

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  • DOI: https://doi.org/10.1007/s12633-018-9781-8

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