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Toxicity of butene-fipronil, in comparison with seven other insecticides, in Leptinotarsa decemlineata and Drosophila melanogaster

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Abstract

The speed of toxic action of an insecticide is an indicator for control efficacy and has considerable practical importance. For agricultural pest control, fast-acting is an important feature for an insecticide to consistently reduce the amount of feeding damage. Butene-fipronil is a novel compound obtained via the structural modification of fipronil. However, information about the toxicity and speed of toxic action is still limited. In the present paper, we compared the toxic feature of butene-fipronil with seven other insecticides, of which imidacloprid and abamectin are slow-acting insecticides, and acephate, endosulfan, methomyl, α-cypermethrin and spinosad are fast-acting insecticides. We found that the contact and stomach toxicities of butene-fipronil were among the highest ever estimated to Leptinotarsa decemlineata and Drosophila melanogaster. The speed of toxic action of butene-fipronil was determined using median lethal time (LT50) at a dose (concentration) equivalent to LD80 values. For L. decemlineata, the values for butene-fipronil, imidacloprid, abamectin, acephate, endosulfan, methomyl, cypermethrin and spinosad were calculated to be 39.9, 36.5, 37.5, 20.2, 22.4, 23.8, 16.4 and 23.1 h, respectively. Those for D. melanogaster were 29.8, 31.5, 29.4, 14.0, 20.3, 18.1, 13.5, and 20.1 h, respectively. ANOVA analysis showed that butene-fipronil, imidacloprid, abamectin had similar LT50 values, whereas acephate, endosulfan, methomyl, spinosad and cypermethrin had comparable LT50 values. Thus, butene-fipronil belongs to slow-acting insecticides. Our results provide more empirical information for butene-fipronil potential application.

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Acknowledgements

This research was supported by the National Basic Research Program of China (973 Program, No. 2010CB126200), the National Natural Sciences Foundation of China (31272047 and 31360442) and a nationally special fund of China for agri-scientific research in the public interest (201103026).

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  1. Education Ministry Key Laboratory of Integrated Management of Crop Diseases and Pests, College of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, China

    Muhammad Shahid Arain, Pin-Jun Wan, Xing-Xing Hu, Muhammad Esmail Abdalla Elzaki & Guo-Qing Li

  2. Research center for Resource Insect and Biochemistry, Gunagdong Institute of Applied Biological Resources, 105 Xingang Road W., 510260, Guangzhou, China

    Muhammad Shahid Arain

  3. Key Laboratory of Bio-Pesticide Innovation and Application of Guangdong Province, College of Agriculture, South China Agricultural University, Guangzhou, China

    Muhammad Shakeel

  4. Entomological Research Institute, Ayub Agricultural Research Institute, Faisalabad, Pakistan

    Muhammad Farooq

  5. Sindh Agricultural University, Tandojam, Pakistan

    Syed Ali Haider Shah

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  1. Muhammad Shahid Arain
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Arain, M.S., Wan, PJ., Shakeel, M. et al. Toxicity of butene-fipronil, in comparison with seven other insecticides, in Leptinotarsa decemlineata and Drosophila melanogaster . Phytoparasitica 45, 103–111 (2017). https://doi.org/10.1007/s12600-016-0560-z

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