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Optimal left ventricular diameter measurement in subjects with sigmoid septum: comparison with three-dimensional left ventricular volume

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Abstract

Background

The purpose of this study was to determine the most appropriate measurement of left ventricular (LV) end-diastolic diameter for subjects with the sigmoid septum (SS) by measuring the LV end-diastolic diameter at the base and mid-ventricle and by examining the relationship between these measurements and the three-dimensional (3D) echocardiographic LV end-diastolic volume.

Methods

In 91 patients who underwent echocardiography for screening cardiovascular abnormalities, the aorto-septal angle (ASA) was measured as an index of the sigmoid septum. LV end-diastolic diameter was measured at the base and mid-ventricular level (DDbase and DDmid, respectively), and their average value was calculated (DDavg). By using 3D echocardiography, LV end-diastolic volume (EDV3D) was measured.

Results

Among 91 patients, 48 patients had narrow ASA (< 120 degrees) and were divided into the sigmoid septum (SS) group, and the remaining 43 patients were divided into the non-SS group. In the SS group, all DDbase, DDmid, and DDavg were significantly correlated with EDV3D (r = 0.59, 0.80, and 0.76, respectively), and the correlation coefficient between DDbase and EDV3D was significantly lower than that between DDmid and EDV3D (p < 0.01). On the other hand, in the non-SS group, all DDbase, DDmid, and DDavg were significantly correlated with EDV3D (r = 0.77, 0.85, and 0.84, respectively), and the correlation coefficient between DDbase and EDV3D was statistically comparable to that between DDmid and EDV3D (p = 0.12). ASA was significantly correlated with the difference of DDmid minus DDbase (r =  − 0.71, p < 0.001).

Conclusions

In patients with SS, DDmid and DDavg were well reflected the 3D echocardiographic LV end-diastolic volume.

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Data availability

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to ethical restrictions.

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Authors and Affiliations

  1. Department of Clinical Laboratory Sciences, Faculty of Health Sciences, Japan Healthcare University, Tsukisamu Higashi 3-Jo 11-1-50, Toyohira-Ku, Sapporo, 062-0053, Japan

    Kazunori Okada, Masahiro Nakabachi, Yasuhiro Hayashi & Masaaki Shinagawa

  2. Kitanodai Clinic, Medical Corporation Hokuseki Group, Kitahiroshima, Japan

    Ayaka Yoshikawa, Kosuke Tsujita & Yoichi Sakamoto

Authors
  1. Kazunori Okada
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  2. Masahiro Nakabachi
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  3. Yasuhiro Hayashi
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  4. Masaaki Shinagawa
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  5. Ayaka Yoshikawa
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  6. Kosuke Tsujita
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  7. Yoichi Sakamoto
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Correspondence to Kazunori Okada.

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Ethical approval

All procedures followed were following the ethical standards of the responsible committee on human experimentation and with the Helsinki Declaration of 1964 and later versions. This study was approved as a retrospective observational study by the Research Ethics Committee of Japan Healthcare University (R04-7). As all examinations were performed within the scope of medical care, obtaining informed consent was waived. Instead of obtaining informed consent, the objectives and methods of the present study were shared with the public through a physical bulletin board; patients who did not wish to participate could request their data to be removed from the study.

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Okada, K., Nakabachi, M., Hayashi, Y. et al. Optimal left ventricular diameter measurement in subjects with sigmoid septum: comparison with three-dimensional left ventricular volume. J Echocardiogr 22, 41–47 (2024). https://doi.org/10.1007/s12574-023-00626-8

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  • DOI: https://doi.org/10.1007/s12574-023-00626-8

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