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Assessment of atria function after percutaneous closure of atrial septal defect using 2D speckle tracking echocardiography

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Abstract

Background

Percutaneous occlusion of atrial septal defect (ASD) has recently become a standard therapeutic strategy, but little is known about atria function thereafter. Strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) is considered to be a new tool to assess myocardial function.

Methods

This study aimed to evaluate atria function by quantifying longitudinal strain in patients with chronic RV volume overload due to ASD before and after percutaneous closure using 2D-STE. 28 consecutive patients underwent percutaneous closure of ASD (18 female, 10 male) were examined, clinical and echocardiographic evaluation one day before, 1 day, and one month after percutaneous closure of ASD. Peak longitudinal systolic strain and strain rate of both atria were analyzed by 2D-STE.

Results

Mean age of the patients was 15.07 ± 8.39 years; mean diameter of ASD was 16.01 ± 2.78 mm; left atrium (LA) diameter significantly increased after ASD closure; and peak longitudinal strain of RA increased significantly one day and one month after ASD closure (48. 77 ± 4.40, vs.55.36 ± 3.70 and, vs. 62.13 ± 3.81%, p = 0.001). LA longitudinal strain significantly decreased after ASD closure (42.55 ± 4.57, vs. 34.79 ± 3.20%, p = 0.001). Furthermore, negative correlation was found between the size of the ASD and delta LA systolic strain and strain rate.

Conclusions

2D-STE can be considered a feasible and simple technique for assessment of atrial deformation in ASD patients, and it useful to assess the effect of percutaneous ASD closure on atrial reservoir function by measuring peak atrial longitudinal strain.

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Abbreviations

ASD:

Atrial septal defect

RA:

Right atrium

2D:

Two dimensional

LV:

Left ventricle

RV:

Right ventricle

LVEF:

Left ventricular ejection fraction

STE:

Speckle tracking echocardiography

SVC:

Superior vena cava

IVC:

Inferior vena cava

RVOT:

Right ventricular outflow tract

LVOT:

Left ventricular out flow tract

VTI:

Velocity time integral

TV:

Tricuspid valve

TAPSE:

Tricuspid annular plane systolic excursion

FW:

Free wall

IAS:

Intra atrial septum

ROI:

Region of interest

TEE:

Trans esophageal echocardiography

SPSS:

Statistical Program for Social Science

SD:

Standard deviation

ANOVA:

A one-way analysis of variance

S:

Strain

SR:

Strain rate

TDI:

Tissue Doppler imaging

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Funding

This study was not funded.

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Authors and Affiliations

  1. Cardiovascular Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt

    Wafaa S. El-Sherbeny & Suzan B. Elhefnawy

Authors
  1. Wafaa S. El-Sherbeny
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  2. Suzan B. Elhefnawy
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Correspondence to Wafaa S. El-Sherbeny.

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Wafaa S. El-Sherbeny and Susan B. Elhefnawy declare that they have no conflict of interest.

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This study was approved by the Ethics Committee in the Faculty of Medicine, Tanta University.

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Informed consent was obtained from all patients included in this study.

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El-Sherbeny, W.S., Elhefnawy, S.B. Assessment of atria function after percutaneous closure of atrial septal defect using 2D speckle tracking echocardiography. J Echocardiogr 20, 33–41 (2022). https://doi.org/10.1007/s12574-021-00546-5

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  • DOI: https://doi.org/10.1007/s12574-021-00546-5

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