Abstract
Although arterial variations in the upper limb are usually found during anatomical dissections and clinical practice, multiple arterial variations associated with nervous variations along the limb is rare and clinically relevant. This paper described a combined anatomical variation involving the neurovasculature in the upper limb. A left upper limb dissection of a male cadaver with approximately 50–60 years of age, fixed in 10% formalin, was performed. During the dissection was observed, the brachial artery ending in the middle third of the arm in three branches: a nutritional branch for the biceps brachii muscle, a “lateral brachial artery” and a “medial brachial artery”, which became, after unusual paths crossing over the cubital fossa, the ulnar artery and the radial artery, respectively. Radial and ulnar artery demonstrated several unusual anastomotic branches, respectively, and an anastomotic arch around the biceps brachii muscle tendon. Such combined anatomical variation is unique and relevant for clinical and surgical practice.
Similar content being viewed by others
References
Adachi B (1928) Das Arteriensystem der Japaner. Bd I, Kenkyusha, Kyoto
Bergman H, Afifi A, Miyauchi R (2006) Anatomy atlases: illustrated encyclopedia of human anatomic variations. Part II: cardiovascular system. https://www.anatomyatlases.org/AnatomicVariants/Cardiovascular/Media/C.shtml. (Accessed 21 May 2020)
Brown MJ, Edstrom LE, Zienowicz RJ (1999) A symptomatic radial artery anomaly and its surgical treatment. J Hand Surg Am 24:178–181. https://doi.org/10.1053/jhsu.1999.jhsu24a0178
Chakravarthi KK (2012) Unusual unilateral muscular variations of the flexor compartment of forearm and hand- a case report. Internat J Med Health Sci 1:93–98
Cherukupalli C, Dwivedi A, Dayal R (2007) High bifurcation of brachial artery with acute arterial insufficiency: a case report. Vasc Endovascular Surg 41:572–574. https://doi.org/10.1177/1538574407305798
Claassen H, Schmitt O, Wree A, Schulze M (2016) Variations in brachial plexus with respect to concomitant accompanying aberrant arm arteries. Ann Anat 208:40–48. https://doi.org/10.1016/j.aanat.2016.07.007
Diz JC, Ares X, Tarrazo AM et al (1998) Bilateral superficial radial artery at the wrist. Acta Anaesthesiol Scand 42:1020. https://doi.org/10.1111/j.1399-6576.1998.tb05367.x
Durgun B, Yücel AH, Kizilkanat ED, Dere F (2002) Multiple arterial variation of the human upper limb. Surg Radiol Anat 24:125–128. https://doi.org/10.1007/s00276-002-0011-z
Honma S, Tokiyoshi A, Kawai K et al (2008) Radial artery running beneath the biceps tendon and its interrelation between the radial recurrent arteries. Anat Sci Int 83:232–238. https://doi.org/10.1111/j.1447-073X.2008.00231.x
Ikeda K, Yokoyama M, Okada K, Tomita T (1999) Obstruction of the radial artery passing beneath the biceps brachii tendon - a case report. Hand Surg 4:101–103. https://doi.org/10.1142/s0218810499000083
Klimek-Piotrowska W, Pacholczak R, Walocha J (2013) Multiple variations of the arterial pattern in upper extremities: a case report and embryological pathogenesis. Clin Anat 26:1031–1035. https://doi.org/10.1002/ca.22171
Lippert H, Pabst R (1985) Arterial variations in man: classification and frequency. Bergmann-Verlag München, J.F
Ljubomudroff A (1927) Zur Morphologie der Arterienanastomosen in der Fossa cubiti. Z Anat Entwicklungs 84:795–813
Quain R (1844) The anatomy of the arteries of the human body with its applications to pathology and operative surgery In lithographic drawings with practical commentaries. Anato Collection Plates 1:1522–1867. https://anatomia.library.utoronto.ca/islandora/object/anatomia%3ARBAI075. (Accessed 14 Apr 2020)
Rodríguez-Baeza A, Nebot J, Ferreira B et al (1995) An anatomical study and ontogenetic explanation of 23 cases with variations in the main pattern of the human brachio-antebrachial arteries. J Anat 187(Pt 2):473–479
Rodríguez-Niedenführ M, Burton GJ, Deu J, Sañudo JR (2001a) Development of the arterial pattern in the upper limb of staged human embryos: normal development and anatomic variations. J Anat 199:407–417. https://doi.org/10.1046/j.1469-7580.2001.19940407.x
Rodríguez-Niedenführ M, Vázquez T, Nearn L et al (2001b) Variations of the arterial pattern in the upper limb revisited: a morphological and statistical study, with a review of the literature. J Anat 199:547–566. https://doi.org/10.1046/j.1469-7580.2001.19950547.x
Standring S (2015) Gray’s Anatomy: The anatomical basis of clinical practice, 41e, Edição: 41. Elsevier, New York
Tsoucalas G, Eleftheriou A, Panagouli E (2020) High bifurcation of the brachial artery: an embryological overview. Cureus 12:e7097. https://doi.org/10.7759/cureus.7097
Tubbs R, Shoja M, Loukas M (2016) Bergman’s comprehensive encyclopedia of human anatomic variation, 1st edn. John Wiley & Sons Inc, New Jersey
Acknowledgments
The authors greatly appreciate the technicians of the Department of Morphology (Universidade Federal do Espirito Santo) for their assistance with the materials. We would like to express gratitude for the anonymous individual who generously donated his body so that this study could be carried out.
Funding
The authors have no funding to report.
Author information
Authors and Affiliations
Contributions
All authors contributed to the study conception, design, and approved the final manuscript. JHFL performed material preparation and dissection. JSB carry out the data collection, data interpretation, and supervised the work. JGA reviewed the literature, contributed to data analysis, and wrote the first draft of the manuscript.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Alexander, J.G., de Fúcio Lizardo, J.H. & da Silva Baptista, J. Multiple arterial variations in the upper limb: description and clinical relevance. Anat Sci Int 96, 310–314 (2021). https://doi.org/10.1007/s12565-020-00569-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12565-020-00569-5