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Innovative aspects of protein stability in ionic liquid mixtures

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Abstract

Mixtures of ionic liquids (ILs) have attracted our attention because of their extraordinary performances in extraction technologies and in absorbing large amount of CO2 gas. It has been observed that when two or more ILs are mixed in different proportions, a new solvent is obtained which is much better than that of each component of ILs from which the mixture is obtained. Within a mixture of ILs, several unidentified interactions occur among several ions which give rise to unique solvent properties to the mixture. Herein, in this review, we have highlighted the utilization of the advantageous properties of the IL mixtures in protein stability studies. This approach is exceptional and opens new directions to the use of ILs in biotechnology.

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Acknowledgements

We gratefully acknowledge the Council of Scientific and Industrial Research, New Delhi, India, through the Grant No. 01(2871)/17/EMR-II) for financial support.

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  1. Department of Chemistry, University of Delhi, Delhi, 110007, India

    Awanish Kumar & Pannuru Venkatesu

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  1. Awanish Kumar
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  2. Pannuru Venkatesu
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Correspondence to Pannuru Venkatesu.

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Awanish Kumar declares that he has no conflicts of interest. Pannuru Venkatesu declares that he has no conflicts of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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This article is part of a Special Issue on “Ionic Liquids and Biomolecules” edited by Antonio Benedetto and Hans-Joachim Galla.

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Kumar, A., Venkatesu, P. Innovative aspects of protein stability in ionic liquid mixtures. Biophys Rev 10, 841–846 (2018). https://doi.org/10.1007/s12551-018-0411-x

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