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Estradiol and Women’s Health: Considering the Role of Estradiol as a Marker in Behavioral Medicine

  • Special Issue: Salivary Bioscience
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Abstract

The sex hormone estradiol, as measured through saliva, represents a non-invasive and cost-effective approach to understanding the influence of hormonal factors on physical and psychological well-being among women. Estradiol levels dramatically change at hormonal transitions, such as puberty, menopause, and postpartum. It is at these transitions where women are at increased risk for psychological and somatic distress. Salivary estradiol also has implications for decision-making and has been broadly associated with engagement in health-compromising behaviors which can influence women’s ability to cope with and manage chronic health conditions. This review summarizes the evidence for salivary estradiol as a marker of physical and psychological health, and discusses practical information regarding saliva collection and assay. The overall intent is to expand and clarify knowledge of the relation between changes in salivary estradiol and women’s health as well as to provide a means of integrating salivary estradiol into future behavioral medicine research.

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Authors and Affiliations

  1. College of Humanities & Science, Thomas Jefferson University, 4201 Henry Avenue, Philadelphia, PA, 19144, USA

    Jenna K. Rieder

  2. Section on Behavioral Oncology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    Katie Darabos

  3. University of Nevada, Reno, Reno, NV, USA

    Mariann R. Weierich

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  1. Jenna K. Rieder
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Rieder, J.K., Darabos, K. & Weierich, M.R. Estradiol and Women’s Health: Considering the Role of Estradiol as a Marker in Behavioral Medicine. Int.J. Behav. Med. 27, 294–304 (2020). https://doi.org/10.1007/s12529-019-09820-4

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