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Standards of care for Kasabach−Merritt phenomenon in China

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Abstract

Kasabach−Merritt phenomenon (KMP) is a rare disease that is characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by kaposiform hemangioendothelioma or tufted hemangioma. This condition primarily occurs in infants and young children, usually with acute onset and rapid progression. This review article introduced standardized recommendations for the pathogenesis, clinical manifestation, diagnostic methods and treatment process of KMP in China, which can be used as a reference for clinical practice.

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Authors and Affiliations

  1. Department of Pediatric Surgery, Children’s Hospital of Fudan University, Shanghai, 201102, China

    Wei Yao & Kai Li

  2. Special Department of Vascular Anomalies, Tumor Hospital of Linyi City, Linyi, 276001, China

    Ke-Lei Li, Zhong-Ping Qin & Mao-Zhong Tai

  3. Department of Oral and Maxillofacial Surgery, Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China

    Jia-Wei Zheng

  4. Department of Intervention Therapy, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China

    Xin-Dong Fan

  5. Department of Dermatology, Beijing Children’s Hospital Affiliated to Capital Medical University, Beijing, 100045, China

    Lin Ma, Li Wei & Li Li

  6. Department of Infantile Hemangioma, Gastrointestinal and Neonatal Surgery, Children’s Hospital of Chongqing Medical University, Chongqing, 400014, China

    De-Kai Zhou

  7. Department of Oncology, People’s Hospital of Linyi Economic Development Zone, Linyi, 276023, China

    Xue-Jian Liu

  8. Department of Pediatric Surgery, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China

    Jin-Hu Wang

  9. Department of Pediatric Surgery, West China Hospital, Sichuan University, Chendu, 610041, China

    Yi Ji

  10. Department of Pediatric Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumchi, 830001, China

    Lin Zhou

  11. Department of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China

    Hai-Jin Huang

  12. Department of Pediatric Surgery, Fujian Provincial Hospital, Fuzhou, 350001, China

    Xiao-Yun Gao

  13. Department of Pediatric Surgery, Children’s Hospital of Soochow University, Suzhou, 215025, China

    Zhi-Jian Huang

  14. Department of Pediatric Surgery, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China

    Song Gu

  15. Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China

    He-Ying Yang

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  1. Wei Yao
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Contributions

YW and LKL contributed equally to this paper. They design, acquisition, analysis and draft the manuscript; QZP contributed to conception, design, acquisition data of the manuscript; LK contributed to conception, design, acquisition data of the manuscript; ZJW contributed to conception, design, acquisition data of the manuscript; FXD contributed to revise the manuscript contributed to acquisition data of the manuscript; ML contributed to analysis and interpretation of data and revise the manuscript; ZDK contributed to analysis and interpretation of data and revise the manuscript; LXJ contributed to acquisition data of the manuscript; WL contributed to acquisition data of the manuscript; LL contributed to acquisition data of the manuscript; TMZ contributed to acquisition data of the manuscript; WJH contributed to acquisition data of the manuscript; JY contributed to analysis and interpretation of data; ZL contributed to analysis and interpretation of data; HHJ contributed to analysis and interpretation of data; GXY contributed to analysis and interpretation of data; HZJ contributed to analysis and interpretation of data; GS contributed to analysis and interpretation of data; YHY contributed to analysis and interpretation of data.

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Correspondence to Zhong-Ping Qin.

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Yao, W., Li, KL., Qin, ZP. et al. Standards of care for Kasabach−Merritt phenomenon in China. World J Pediatr 17, 123–130 (2021). https://doi.org/10.1007/s12519-020-00379-9

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