Skip to main content

Advertisement

SpringerLink
Log in

Hard Palate Metastasis from Rectal Adenocarcinoma

  • Case Report
  • Published:
Clinical Journal of Gastroenterology Aims and scope Submit manuscript

Abstract

The most common sites of metastasis from colorectal cancer are liver, lungs, and peritoneum. Oral cavity metastasis is extremely rare, accounting for only 1–2% of all oral cancers. We report the case of a 71-year-old male who presented with hard palate metastasis 20 months after his initial diagnosis for T4N1M1 rectal adenocarcinoma according to the UICC TNM classification. To the best of our knowledge, hard palate metastasis from colorectal cancer has never been previously reported in the literature. The hard palate metastasis deteriorates oral function, resulted in unfavorable prognosis. Early detection of oral cavity metastasis could lead to the opportunities for additional treatment and improve outcomes following treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig.4
Fig. 5
Fig. 6

Similar content being viewed by others

Abbreviations

CRC:

Colorectal cancer

CEA:

Carcinoembryonic antigen

CA19-9:

Carbohydrate antigen 19–9

CT:

Computed tomography

CAPOX:

Capecitabine and L-OHP

IRIS:

S-1 and CPT-11

References

  1. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2020;71(3):209–49.

    Article  Google Scholar 

  2. Siegel RL, Miller KD, Goding Sauer A, et al. Colorectal cancer statistics, 2020. CA Cancer J Clin. 2020;70:145–64.

    Article  Google Scholar 

  3. Hess KR, Varadhachary GR, Taylor SH, et al. Metastatic patterns in adenocarcinoma. Cancer. 2006;106:1624–33.

    Article  Google Scholar 

  4. Khawaja MR, Minturn JT, Spittler AJ, et al. Ocular metastasis of colorectal cancer: an uncommon presentation of a common malignancy. Hematol Oncol Stem Cell Ther. 2015;8:176–80.

    Article  Google Scholar 

  5. Huang YJ, Chen CT, Hsieh YW et al (2020) Rectal cancer with synchronous tonsillar metastasis: a case report and literature review. Ear Nose Throat J. https://doi.org/10.1177/0145561320971928

    Article  PubMed  Google Scholar 

  6. Liu YH, Lin BB, Lv SX. Nasopharyngeal metastasis from colorectal cancer: a case report. Ann Palliat Med. 2021;10:4911–4816.

    Article  Google Scholar 

  7. Brierley J, Gospodarowicz MK, Wittekind C. TNM classification of malignant tumours. Chichester: John Wiley & Sons Inc; 2017.

    Google Scholar 

  8. van der Waal RI, Buter J, van der Waal I. Oral metastases: report of 24 cases. Br J Oral Maxillofac Surg. 2003;41:3–6.

    Article  Google Scholar 

  9. Rao DN, Shroff PD, Chattopadhyay G, et al. Survival analysis of 5595 head and neck cancers–results of conventional treatment in a high-risk population. Br J Cancer. 1998;77:1514–8.

    Article  CAS  Google Scholar 

  10. Rutkowska M, Hnitecka S, Nahajowski M, et al. Oral cancer: the first symptoms and reasons for delaying correct diagnosis and appropriate treatment. Adv Clin Exp Med. 2020;29:735–43.

    Article  Google Scholar 

  11. Speight PM, Farthing PM. The pathology of oral cancer. Br Dent J. 2018;225:841–7.

    Article  CAS  Google Scholar 

  12. Salvador JC, Rosa D, Rito M, et al. Atypical mandibular metastasis as the first presentation of a colorectal cancer. BMJ Case Rep. 2018;2018:bcr2018225094.

    Article  Google Scholar 

  13. Riihimaki M, Hemminki A, Sundquist J, et al. Patterns of metastasis in colon and rectal cancer. Sci Rep. 2016;6:29765.

    Article  Google Scholar 

Download references

Acknowledgements

We have no acknowledgments.

Author information

Authors and Affiliations

  1. Department of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka, 545-8585, Japan

    Atsushi Sugimoto

  2. Department of Surgery, Aomatsu Memorial Hospital, 876-1 Kamikawaraya, Izumisano, Osaka, 598-0001, Japan

    Atsushi Sugimoto, Soichiro Hiramatsu & Keiho Aomatsu

  3. Department of Surgery Center, Fuchu Hospital, Hikocho, Izumi, Osaka, 594-0076, Japan

    En Wang

Authors
  1. Atsushi Sugimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Soichiro Hiramatsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. En Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Keiho Aomatsu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Atsushi Sugimoto.

Ethics declarations

Competing of Interests

The authors declare that they have no conflict of interest.

Human rights

All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its subsequent amendments.

Informed Consent

Informed consent was obtained from all patients for being included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sugimoto, A., Hiramatsu, S., Wang, E. et al. Hard Palate Metastasis from Rectal Adenocarcinoma. Clin J Gastroenterol 15, 708–711 (2022). https://doi.org/10.1007/s12328-022-01630-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12328-022-01630-8

Keywords

Search

Navigation