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Conversion surgery for recurrent hepatic angiosarcoma after systemic chemotherapy with paclitaxel

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Abstract

A 67-year-old man presented with hemorrhagic shock due to the rupture of hepatic tumor and underwent emergency partial resection of the right liver. Pathological examination revealed hepatic angiosarcoma with involvement in its surgical margin. Six months after the operation, disease recurrence was detected, and he was referred to our hospital for second opinion. CT revealed tumors at the liver cut surface and left lateral segment. The tumor at the liver cut surface abutted to the common bile duct and the portal vein. The tumor was deemed unresectable, and systemic chemotherapy with 4 courses of weekly paclitaxel was given with excellent response. Then, we performed partial liver resection of S4 and S1 with remnant right liver and middle hepatic vein, and wedge resection for the metastatic lesion of segment 3 as a conversion surgery. He developed a grade B bile leakage postoperatively and was discharged on postoperative day 28. He remained disease free for 8 months after the operation.

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Authors and Affiliations

  1. Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Yuta Ushida, Takafumi Sato, Tomotaka Kato, Hiromichi Ito, Yosuke Inoue, Yoshihiro Ono, Atsushi Oba & Yu Takahashi

  2. Department of Pathology, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Yasuyuki Shigematsu

  3. Division of Pathology, Cancer Institute, The Japanese Foundation for Cancer Research, 3-8-31, Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Yasuyuki Shigematsu

  4. Department of Surgery, Chiba Rosai Hospital, 2-16, Tatsumidai Higashi, Ichihara-shi, Chiba, 290-0003, Japan

    Takeshi Suzuki

Authors
  1. Yuta Ushida
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  2. Takafumi Sato
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  3. Tomotaka Kato
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  4. Yasuyuki Shigematsu
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  5. Hiromichi Ito
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  6. Takeshi Suzuki
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  7. Yosuke Inoue
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  8. Yoshihiro Ono
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  9. Atsushi Oba
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  10. Yu Takahashi
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Correspondence to Takafumi Sato.

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The authors have no conflicts of interest to declare and received no financial support for this report.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from this patient to be included in the study.

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Ushida, Y., Sato, T., Kato, T. et al. Conversion surgery for recurrent hepatic angiosarcoma after systemic chemotherapy with paclitaxel. Clin J Gastroenterol 15, 427–432 (2022). https://doi.org/10.1007/s12328-021-01569-2

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  • DOI: https://doi.org/10.1007/s12328-021-01569-2

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