Abstract
A 65-year-old man with ulcerative colitis presented with aggravated diabetes. Computed tomography showed two masses in the body and tail of the pancreas. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) was performed, with histopathological findings suggesting autoimmune pancreatitis (AIP). Type-2 AIP was suspected, and administration of prednisolone was initiated. The pancreatic masses had disappeared after the treatment. In this case, EUS-FNA was effective for the diagnosis of type-2 AIP. The two-lesion mass formation observed here is a rare presentation of the disease. In patients with a history of ulcerative colitis, the possibility of late-onset type-2 AIP should be kept in mind.
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References
Yoshida K, Toki F, Takeuchi T, et al. Chronic pancreatitiscausedby an autoimmune abnormality. Proposal of the concept of autoimmune pancreatitis. Dig Dis Sci. 1995;40:1561–8.
Zamboni G, Lüttges J, Capelli P, et al. Histopathological features of diagnostic and clinical relevance in autoimmune pancreatitis:a study on 53 resection specimens and 9 biopsy specimens. Virchows Arch. 2004;445:552–63.
Notohara K, Burgart LJ, Yadav D, et al. Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration:clinicopathologic features of 35 cases. Am J Surg Pathol. 2003;27:1119–27.
Shimosegawa T, Chari ST, Frulloni L, et al. International consensus diagnostic criteria for autoimmunepancreatitis:guidelinesoftheInternational Association of Pancreatology. Pancreas. 2011;40:352–8.
Kamisawa T, Chari ST, Giday SA, et al. Clinical profile of autoimmune pancreatitis and its histological subtypes: an international multicenter survey. Pancreas. 2011;40:809–14.
Hart PA, Kamisawa T, Brugge WR, et al. Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis. Gut. 2013;62:1771–6.
Kanno A, Masamune A, Fujishima F, et al. Diagnosis of autoimmune pancreatitis by EUS-guided FNAusinga22-gaugeneedle:aprospective multicenter study. Gastrointest Endosc. 2016;84:797–804.
Ishikawa T, Itoh A, Kawashima H, et al. Endoscopicultrasound-guidedfine needle aspiration in the differentiation of type 1 and type 2 autoimmune pancreatitis. World J Gastroenterol. 2012;18:3883–8.
Morishima T, Kawashima H, Ohno E, et al. Prospective multicenter study on the usefulness of EUS-guidedFNAbiopsyforthediagnosisofautoimmune pancreatitis. Gastrointest Endosc. 2016;84:241–8.
Kanno A, Ishida K, Hamada S, et al. Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria. Gastrointest Endosc. 2012;76:594–602.
Yano M, Nishikawa M, Asai J, et al. A case of definitive type 2 autoimmune pancreatitis diagnosed using endoscopic ultrasound-guided fine needle aspiration biopsy]. Nihon Shokakibyo Gakkai Zasshi. 2014;111:2181–9.
Kurita A, Yasukawa S, Zen Y, et al. Comparison of a 22-gauge Franseen-tip needle with a 20-gauge forward-bevel needle for the diagnosis of type 1 autoimmune pancreatitis: a prospective, randomized, controlled, multicenter study (COMPAS study). Gastrointest Endosc. 2020;91:373–81.
Nishimori I, Tamakoshi A, Kawa S, et al. Influence of steroid therapy on the course of diabetes mellitus in patients with autoimmune pancreatitis: findings from a nationwide survey in Japan. Research Committee on Intractable Pancreatic Diseases, the Ministry of Health and Welfare of Japan. Pancreas. 2006;32:244–8.
Miyazawa M, Takatori H, Shimakami T, et al. Prognosis of type 1 autoimmune pancreatitis after corticosteroid therapy-induced remission in terms of relapse and diabetes mellitus. PLoS ONE. 2017;12:e0188549.
Detlefsen S, Löhr M, Drewes AM, et al. Current concepts in the diagnosis and treatment of type 1 and type 2 autoimmune pancreatitis. Recent Pat Inflamm Allergy Drug Discov. 2011;5:136–49.
Okazaki K, Chari ST, Frulloni L, et al. International consensus for the treatment of autoimmune pancreatitis. Pancreatology. 2017;17:1–6.
Sah RP, Chari ST, Pannala R, et al. Differences in clinical profile and relapse rate of type 1 versus type 2 autoimmune pancreatitis. Gastroenterology. 2010;139:140–8.
Hota P, Patel T, Zhao X, et al. A rare multifocal pattern of type 2 autoimmune pancreatitis with negative igg4: a potential diagnostic pitfall that may mimic multifocal pancreatic adenocarcinoma. Case Rep Gastroenterol. 2018;12:46–55.
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YM diagnosed, treated this case, and drafted this article. AS, KO, MN, SH, SK, YY, KI, and ES treated this case. SS supervised the process of drafting this article.
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Yoshihide Matsumoto, Akiko Shimizu, Kento Ogawa, Masaharu Nakamura, Shinya Hoki, Shigenobu Kuroki, Yasumichi Yano, Kozo Ikuta, Eri Senda and Seiji Shio declare that they have no conflict of interest.
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Matsumoto, Y., Shimizu, A., Ogawa, K. et al. Late-onset type-2 autoimmune pancreatitis with two mass lesions diagnosed by endoscopic ultrasound-guided fine-needle aspiration. Clin J Gastroenterol 14, 899–904 (2021). https://doi.org/10.1007/s12328-021-01364-z
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DOI: https://doi.org/10.1007/s12328-021-01364-z