Abstract
Noroviruses cause epidemic and sporadic acute gastroenteritis in both children and adults. We report a rare case of intestinal necrosis due to norovirus gastroenteritis in a healthy adult. A 47-year-old man presented with worsening abdominal pain, diarrhea, vomiting, and abdominal fullness. Physical examination revealed abdominal distension and diffuse tenderness. Contrast-enhanced computed tomography revealed intestinal distention, pneumatosis, and portal venous gas, findings suggestive of intestinal necrosis. Norovirus genome was detected in his stools using the RT-PCR method. Upon laparotomy, a segment of necrotic bowel 170 cm from the ileocecal valve was identified, and the lesion was resected with an end ileostomy. The patient‘s recovery was uneventful, and he was transferred to another hospital on the 7th post-operative day. Ileostomy closure was performed one month after the first surgery at the transfer hospital. He had no recurrent episodes.
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References
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention. Updated norovirus outbreak management and disease prevention guidelines. MMWR Recomm Rep. 2011;60:1–18.
Glass RI, Noel J, Ando T, et al. The epidemiology of enteric caliciviruses from humans: a reassessment using new diagnostics. J Infect Dis. 2000;181:254–61.
Westhoff TH, Vergoulidou M, Loddenkemper C, et al. Chronic norovirus infection in renal transplant recipients. Nephrol Dial Transpl. 2009;24:1051–3.
Turcios-Ruiz RM, Axelrod P, St John K, et al. Outbreak of necrotizing enterocolitis caused by norovirus in a neonatal intensive care unit. J Pediatr. 2008;153:339–44.
Bagci S, Eis-Hübinger AM, Yassin AF, et al. Clinical characteristics of viral intestinal infection in preterm and term neonates. Eur J Clin Microbiol Infect Dis. 2010;29:1079–84.
Pawa N, Vanezis AP, Tutton MG. Spontaneous bowel perforation due to norovirus: a case report. Case J. 2009;27:9101.
Zenda T, Kaneko S, Noriki S. Norovirus gastroenteritis accompanied by ischemic colitis: a case report. Hiroshima J Med Sci. 2010;59(4):83–5.
Jiang X, Wang M, Wang K, et al. Sequence and genomic organization of Norwalk virus. Virology. 1993;195:51–61.
Lowenthal A, Livni G, Amir J, et al. Secondary bacteremia after rotavirus gastroenteritis in infancy. Pediatrics. 2006;117:224–6.
Carneiro NB, Diniz-Santos DR, Amorim C, Galeno C, et al. Shock complicating acute rotavirus-associated diarrhea. Pediatr Infect Dis J. 2006;25:571–2.
Di Biase AM, Petrone G, Conte MP, et al. Infection of human enterocyte-like cells with rotavirus enhances invasiveness of Yersinia enterocolitica and Y. pseudotuberculosis. J Med Microbiol. 2000;49:897–904.
Ruuska T, Vesikari T. Rotavirus disease in Finnish children: use of numerical scores for clinical severity of diarrhoeal episodes. Scand J Infect Dis. 1990;22:259–67.
Givon-Lavi N, Greenberg D, Dagan R. Comparison between two severity scoring scales commonly used in the evaluation of rotavirus gastroenteritis in children. Vaccine. 2008;26:5798–801.
Jennifer M, Newton MD, Christina M, Surawicz MD. Infectious gastroenteritis and colitis In: Stefano G, Haleh V, editors. Diarrhea clinical gastroenterology. New York, Dordrecht, Heidelberg, London: Springer; 2011.
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Conflict of Interest:
Hiromi Yasuda, Yoshiki Okita, Yuhki Imaoka, Hiroyuki Fujikawa, Masaki Ohi, Toshimitsu Araki, Koji Tanaka, Tsunehiko Shigemori, Toshio Kato,Yasuhiko Mohri and Masato Kusunoki declare that they have no conflict of interest.
Human/Animal Rights:
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.
Informed Consent:
Informed consent was obtained from all patients for being included in the study.
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Yasuda, H., Okita, Y., Imaoka, Y. et al. Intestinal necrosis due to norovirus enteritis. Clin J Gastroenterol 8, 10–13 (2015). https://doi.org/10.1007/s12328-014-0540-0
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DOI: https://doi.org/10.1007/s12328-014-0540-0