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Disrupted Rotational Perception During Simultaneous Stimulation of Rotation and Inertia

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Abstract

Two vestibular signals, rotational and inertial cues, converge for the perception of complex motion. However, how vestibular perception is built on neuronal behaviors and decision-making processes, especially during the simultaneous presentation of rotational and inertial cues, has yet to be elucidated in humans. In this study, we analyzed the perceptual responses of 20 participants after pairwise rotational experiments, comprised of four control and four test sessions. In both control and test sessions, participants underwent clockwise and counterclockwise rotations in head-down and head-up positions. The difference between the control and test sessions was the head re-orientation relative to gravity after rotations, thereby providing only rotational cues in the control sessions and both rotational and inertial cues in the test sessions. The accuracy of perceptual responses was calculated by comparing the direction of rotational and inertial cues acquired from participants with that predicted by the velocity-storage model. The results showed that the accuracy of rotational perception ranged from 80 to 95% in the four control sessions but significantly decreased to 35 to 75% in the four test sessions. The accuracy of inertial perception in the test sessions ranged from 50 to 70%. The accuracy of rotational perception improved with repetitive exposure to the simultaneous presentation of both rotational and inertial cues, while the accuracy of inertial perception remained steady. The results suggested a significant interaction between rotational and inertial perception and implied that vestibular perception acquired in patients with vestibular disorders are potentially inaccurate.

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Data Availability

No datasets were generated or analysed during the current study.

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Funding

This study was supported by the Basic Science Research Program through theNational Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (2020R1A2C4002281).

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Authors and Affiliations

  1. Department of Neurology, Catholic University of Korea Eunpyeong St. Mary’s Hospital, Seoul, Republic of Korea

    Ju-Young Lee

  2. Department of Neurology, Yonsei University Severance Hospital, Seoul, Republic of Korea

    So-Yeon Yun

  3. Dizziness Center, Department of Neurology and Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

    Yu-Jin Koo, Jung-Mi Song, Jeong‑Yoon Choi & Ji-Soo Kim

  4. Research Administration Team, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

    Hyo-Jung Kim

  5. Department of Neurology, Seoul National University College of Medicine, Seoul, Korea

    Jeong‑Yoon Choi & Ji-Soo Kim

Authors
  1. Ju-Young Lee
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  2. So-Yeon Yun
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  3. Yu-Jin Koo
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  4. Jung-Mi Song
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Contributions

Dr. Lee and Yun analyzed the data and wrote the draft. Dr. Koo, Mrs. Song, and Dr. HJ Kim performed experiments and analyzed the data. Dr. Choi designed and conceptualized the study, interpreted the data, and wrote the manuscript. Dr. JS Kim analyzed and interpreted the data and revised the manuscript.

Corresponding author

Correspondence to Jeong‑Yoon Choi.

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Ethical Approval

This study followed the tenets of the Declaration of Helsinki and was performed according to the guidelines of Institutional Review Board of Seoul National University Bundang Hospital (B-2007–627-304).

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The authors declare no competing interests.

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Lee, JY., Yun, SY., Koo, YJ. et al. Disrupted Rotational Perception During Simultaneous Stimulation of Rotation and Inertia. Cerebellum (2024). https://doi.org/10.1007/s12311-024-01698-7

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  • DOI: https://doi.org/10.1007/s12311-024-01698-7

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