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Breast cancer screening for women at high risk: review of current guidelines from leading specialty societies

  • Special Feature
  • High-risk screening: up-to-date
  • Published:
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Abstract

The purpose of this article is to overview the existing breast cancer screening guidelines for women at high risk from world-leading specialty societies. Accumulation of evidence and development of accessible genetic testing strategies have changed the idea of breast cancer screening for high-risk women. Personalized tailor-made screening adjusted for risk factors has been conducted in accordance with guidelines. The use of imaging modalities other than mammography including contrast-enhanced MRI and other various strategies for improving screening are discussed. The present review also mentions the existing challenges in high-risk screening and the latest information based on two large-scale studies.

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Abbreviations

ADH:

Atypical ductal hyperplasia

ALH:

Atypical lobular hyperplasia

CDR:

Cancer detection rate

DBT:

Digital breast tomosynthesis

DCE:

Dynamic contrast-enhanced

DCIS:

Ductal carcinoma in situ

DM:

Digital mammography

LCIS:

Lobular carcinoma in situ

MRI:

Magnetic resonance imaging

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Authors and Affiliations

  1. Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA

    Natsuko Onishi

  2. Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto, Japan

    Masako Kataoka

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  1. Natsuko Onishi
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  2. Masako Kataoka
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Correspondence to Natsuko Onishi.

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Onishi, N., Kataoka, M. Breast cancer screening for women at high risk: review of current guidelines from leading specialty societies. Breast Cancer 28, 1195–1211 (2021). https://doi.org/10.1007/s12282-020-01157-1

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