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The Evolving Epidemiology of Sporotrichosis

  • Epidemiological Aspects of Fungal Infection (T Chiller and J Baddley, Section Editors)
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Abstract

Sporotrichosis is an uncommon subcutaneous mycosis found throughout the world. Certain tropical and subtropical areas, in particular South America, have regions of hyperendemic disease. Here, we report on the developing genetic diversity of the genus as well as the epidemiology, from the beginnings of the French and South African epidemics through the modern day outbreak in Brazil. The ongoing Brazilian epidemic has led to the discovery of a new species, Sporothrix brasiliensis, and there have been several other clinical and environmental species identified throughout the globe as well. It remains to be seen, however, just what impact this species diversity has on clinical disease.

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Conflict of Interest

TP McCarty declares no conflicts of interest.

PG Pappas has received research grants from Astellas, Merck, Gillead, T2 Biosystems, and Scynexis, and serves on a scientific advisory board for Merck, Gillead, T2 Biosystems, and Scynexis.

Human and Animal Rights and Informed Consent

All studies by PG Pappas involving animal and/or human subjects were performed after approval by the appropriate institutional review boards. When required, written informed consent was obtained from all participants.

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McCarty, T.P., Pappas, P.G. The Evolving Epidemiology of Sporotrichosis. Curr Fungal Infect Rep 8, 255–261 (2014). https://doi.org/10.1007/s12281-014-0203-0

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