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Geschlechtsdifferenzierte Genexpression

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  • Genregulation
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Abstract

Sexual dimorphism, the difference in morphology, physiology and behavior between males and females, is a widespread phenomenon. Differential gene expression between the sexes, known as sex-biased gene expression, is a major contributor to sexual dimorphism and has been investigated in many diverse species. Here, we discuss how genes with sex-biased expression are defined and identified, and how understanding their special characteristics is important for various fields of biology, ranging from evolution to medicine.

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Correspondence to John Parsch.

Additional information

Sonja Grath 2001–2007 Bioinformatikstudium an der LMU und TU München. 2010 Promotion an der LMU München im Fach Evolutionsbiologie, danach Postdoc an der Universität Münster. Seit 2012 Juniorgruppenleiterin am Lehrstuhl für Evolutionsbiologie der LMU München.

John Parsch 1998 Promotion (PhD) in Molekularer Biologie und Zellbiologie an der Universität Maryland, College Park; danach Postdoc an der Universitäten Rochester, NY, und Harvard, Cambrigde, MD, USA. Seit 2001 Professor für Evolutionäre und Funktionelle Genomik an der LMU München.

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Grath, S., Parsch, J. Geschlechtsdifferenzierte Genexpression. Biospektrum 25, 12–14 (2019). https://doi.org/10.1007/s12268-019-0995-0

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  • DOI: https://doi.org/10.1007/s12268-019-0995-0

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