Abstract
Prokaryotic genomes often contain CRISPR-Cas systems that enable RNAguided defense against viral attacks. Viral genomes were found to encode anti-CRISPR proteins that inactivate specific Cas protein functions. In the last years, a large variety of CRISPR-Cas system components and mechanisms has been uncovered. This diversity highlights the fact that CRISPRCas systems co-evolve with anti-CRISPR measures, but also indicates that they can adopt roles in the cell that extend beyond viral defense.
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Hanna Müller-Esparza Jahrgang 1991. 2009–2015 Biochemiestudium an der Päpstlichen Katholischen Uni - versität von Chile. Seit 2015 Promotion am Max-Planck-Institut für terrestrische Mikrobiologie in Marburg.
Daniel Gleditzsch Jahrgang 1990. 2010–2015 Biologiestudium an der TU Darmstadt. Seit 2016 Promotion am Max-Planck-Institut für terrestrische Mikrobiologie in Marburg.
Lennart Randau Jahrgang 1978. 2002–2006 Promotion am Institut für Mikrobiologie, TU Braunschweig, bei Prof. Dr. D. Jahn. 2006–2010 Postdoc an der Yale University, USA, Molecular Biophysics and Biochemistry, bei Prof. Dr. D. Söll. Seit 2010 Leiter einer unabhängigen Max-Planck-Forschungsgruppe am Max-Planck-Institut für terrestrische Mikrobiologie in Marburg.
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Müller-Esparza, H., Gleditzsch, D. & Randau, L. Vielfältige Genscheren: natürliche Aktivitäten von CRISPR-Cas-Systemen. Biospektrum 24, 704–706 (2018). https://doi.org/10.1007/s12268-018-0978-6
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DOI: https://doi.org/10.1007/s12268-018-0978-6