Skip to main content
SpringerLink
Log in

DNA und RNA — mehr als nur Träger der genetischen Information

  • Nukleinsäuren
  • Published:
BIOspektrum Aims and scope

Abstract

DNA and RNA — the nucleic acids within our cells — are more than information carrier in the flow of genetic information within biological systems. They fulfil very diverse functions in numerous cellular processes, such as the regulation of gene expression and cell signalling, they mediate protein interactions, control enzyme activity, can catalyse chemical reactions and are crucial for cellular immunity. Here, I discuss their multifaceted roles from a nucleic acids perspective.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Harteis S, Schneider S (2014) Making the bend: DNA tertiary structure and protein-DNA interactions. Int J Mol Sci 15:12335–12363

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Cech TR, Steitz JA (2014) The noncoding RNA revolution–trashing old rules to forge new ones. Cell 157:77–94

    Article  PubMed  CAS  Google Scholar 

  3. Storz G, Vogel J, Wassarman KM (2011) Regulation by small RNAs in bacteria: expanding frontiers. Mol Cell 43:880–891

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  4. Wilson RC, Doudna JA (2013) Molecular mechanisms of RNA interference. Annu Rev Biophys 42:217–239

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Wang M, Yu F, Wu W et al. (2017) Circular RNAs: a novel type of non-coding RNA and their potential implications in antiviral immunity. Int J Biol Sci 13:1497–1506

    Article  PubMed  PubMed Central  Google Scholar 

  6. Martin KC, Ephrussi A (2009) mRNA localization: gene expression in the spatial dimension. Cell 136:719–730

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Loenen WA, Dryden DT, Raleigh EA et al. (2014) Highlights of the DNA cutters: a short history of the restriction enzymes. Nucleic Acids Res 42:3–19

    Article  PubMed  CAS  Google Scholar 

  8. Westra ER, Swarts DC, Staals RH et al. (2012) The CRISPRs, they are a-changin’: how prokaryotes generate adaptive immunity. Annu Rev Genet 46:311–339

    Article  PubMed  CAS  Google Scholar 

  9. Hartmann G (2017) Nucleic acid immunity. Adv Immunol 133:121–169

    Article  PubMed  CAS  Google Scholar 

  10. Shi Y (2017) The spliceosome: a protein-directed metalloribozyme. J Mol Biol 429:2640–2653

    Article  PubMed  CAS  Google Scholar 

  11. Jenni S, Ban N (2003) The chemistry of protein synthesis and voyage through the ribosomal tunnel. Curr Opin Struct Biol 13:212–219

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department Chemie, TU München, Garching, Deutschland

    Sabine Schneider

  2. Fakultät für Chemie, Technische Universität München, Lichtenbergstraße 4, D-85748, Garching, Deutschland

    Sabine Schneider

Authors
  1. Sabine Schneider
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sabine Schneider.

Additional information

Sabine Schneider 2007 Promotion an der University of Nottingham, UK. 2007–2010 Postdoktorandin an der LMU München. Seit 2010 unabhängige Forschungsgruppenleiterin an der TU München.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Schneider, S. DNA und RNA — mehr als nur Träger der genetischen Information. Biospektrum 24, 368–371 (2018). https://doi.org/10.1007/s12268-018-0930-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12268-018-0930-9

Search

Navigation