Abstract
Extracellular vesicles (EV) are secreted by most cells and are present in every body fluid. They can be seen as major players in the regulation and communication of cells. They are adressed as therapeutic and diagnostic tool for many disorders including neurodegenerative diseases. Distinct subpopulations of platelet derived EVs have been shown to contain high concentrations of Alzheimer’s disease(AD)-associated proteins e. g. APP, APOE, lipids and miRNAs and thus might contribute actively to the progression of the disease.
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Helmut E. Meyer Biochemiestudium an der Universität Tübingen. 1974–1976 Dißsertation an der Ruhr-Universität Bochum. 1989 Habilitation. 1995 Ernennung zum außerplanmäßigen Professor. 1999–2014 Direktor des Medizinischen Proteom Centers der Ruhr-Universität Bochum, Juni 2010 Ernennung zum Universitätsprofessor der Ruhr-Universität Bochum, 2013–2015 Direktor Biomedical Research, ISAS Dortmund. Seit Juni 2015 Research Associate am ISAS - e.V.
Gerd Schmitz Medizinstudium und Abschluss an der Universität Köln. 1979 Promotion in Klinischer Chemie und Pathobiochemie, 1984 Habilitation für das Fach Klinische Chemie und Laboratoriumsmedizin, 1991–2014 Direktor des Instituts für Laboratoriumsmedizin und Transfusionsmedizin an der Universität Regensburg, 2014 Gründung der LipoConsult GmbH.
Fouzi El Magraoui Biochemiestudium an der Ruhr-Universität Bochum, 2013 Promotion, 2013 Postdoktorand am Medizinischen Proteom Center Bochum, seit 2014 Research Associate am Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V.
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El Magraoui, F., Schmitz, G. & Meyer, H.E. Zirkulierende extrazelluläre Vesikel - die Biomarker der Zukunft?!. Biospektrum 23, 777–778 (2017). https://doi.org/10.1007/s12268-017-0872-7
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DOI: https://doi.org/10.1007/s12268-017-0872-7