Abstract
Metabolic processes, signal transduction, gene regulation, gene and protein expression in biological systems, all are controlled by means of networks. Several bioinformatics approaches have been introduced to infer networks from high-throughput data. But still, most networks are not known in detail for most biological systems. Thus, the question arises whether biological networks can be transferred between species, or whether they are specific for individual contexts: to be, or not to be.
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Robert Pesch Jahrgang 1985. 2004–2010 Informatik-studium (Bachelor und Master) an der Hochschule Bonn-Rhein-Sieg. Seit 2010 Doktorand in der Lehr- und Forschungseinheit Bioinformatik am Institut für Informatik der LMU München.
Ralf Zimmer Jahrgang 1961. 1981–1986 Informatikstudium (Diplom, NF Operations Research) an der Universität Bonn. 1990 Promotion in Informatik und Praktischer Mathematik an der Universität Kiel. 1986–2000 Gruppenleiter Forschungszentrum Informationstechnik Sankt Augustin, 1995 Postdoc am National Institutes of Health (NIH), Bethesda, MD, USA und 1997 Stanford University, CA, USA. Seit 2001 C4-Professor für Praktische Informatik und Bioinformatik an der LMU München.
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Pesch, R., Zimmer, R. To be, or not to be: konservierte eukaryotische Regulationsnetzwerke?. Biospektrum 20, 514–516 (2014). https://doi.org/10.1007/s12268-014-0474-6
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DOI: https://doi.org/10.1007/s12268-014-0474-6