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Gestational Gigantomastia: a Case Report

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Abstract

Gestational gigantomastia (GG) is a rare condition characterized by excessive breast enlargement during pregnancy. Reported incidence ranges from 1 in 28, 000 to 1 in 100, 000 pregnancies worldwide. The etiology of the disease is not yet established, with theories ranging from hormonal imbalances, unregulated immune responses, to hypersensitivity. In this article, we report an extreme case of GG in a 29-year-old pregnant Chinese woman with a total breast weight of 13 kg. There is no laboratory analysis that reveals the cause of this enormous breast enlargement. The severity of the problem is further emphasized by the patient’s breathing and walking problems. Finally, the case was successfully treated by bilateral mastectomies with the free areola–nipple complex graft implantation, followed by two-stage breast reconstruction. The surgery was successful, and the patient had an excellent post-operation recovery course. And this article provides a rare case report and discussion about the surgical approach.

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Data Availability

The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.

References

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Funding

This study has been funded by the Natural Science Foundation of Guangdong Province, 2020A1515010425, and Guangzhou Science, Technology, and Innovation Commission 805275295029.

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Authors and Affiliations

  1. Department of Breast Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26 Yuancun Erheng Road, Tianhe District, Guangzhou, 510655, Guangdong, China

    Qingyu Yang, Ziteng Liu, Xiaoyan Fu & Haiyan Li

  2. Zhongshan School of Medicine, Sun Yat-sen University, Guangdong, Guangzhou, China

    Ziyu Zhang

Authors
  1. Qingyu Yang
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  2. Ziyu Zhang
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  3. Ziteng Liu
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  4. Xiaoyan Fu
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  5. Haiyan Li
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Contributions

Qingyu Yang contributed to the conception and design of the study. Ziyu Zhang and Ziteng Liu contributed to the acquisition of clinical data and data analysis. Haiyan Li contributed to the conception and the design of the study. All authors contributed to the drafting of the manuscript, critical reversion, and approval of the final version of the manuscript.

Corresponding author

Correspondence to Haiyan Li.

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No ethical approval was needed for this study as this is a case report.

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The patient gave informed written consent to publish her case (including the publication of images).

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The authors declare no competing interests.

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Cite this article

Yang, Q., Zhang, Z., Liu, Z. et al. Gestational Gigantomastia: a Case Report. Indian J Surg 85, 1461–1463 (2023). https://doi.org/10.1007/s12262-023-03720-4

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  • DOI: https://doi.org/10.1007/s12262-023-03720-4

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