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Comparison of Systemic Inflammatory Response After Total Extraperitoneal Repair and Lichtenstein Repair of Inguinal Hernia

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Abstract

Despite advances and researches in the field of surgery, there still remains some controversy regarding the inflammatory changes seen in various repair procedures for hernia. The aim of the study was assessment of the systemic inflammatory response (SIR) intensity by measuring the blood serum levels of high sensitivity C-reactive protein (hsCRP), Interleukin-6 (IL-6) and total leukocyte counts of patients. The estimations were done before and after the patient underwent either open Lichtenstein or endoscopic TEP (total extraperitoneal repair) inguinal hernia repair. This is a prospective observational study. Eighty patients of unilateral uncomplicated inguinal hernia were included. Patients were divided into two groups as endoscopic total extraperitoneal repair (TEP) and Lichtenstein repair. The patient selection was random. Serum markers for SIR were measured prior to and 24 h post-surgery. Total extraperitoneal repair (TEP) and open Lichtenstein inguinal hernia repair both cause a significant systemic inflammatory response in the body. The rise in serum markers for SIR post-surgery was statistically significant in both the groups. The rise in serum hsCRP and IL-6 concentrations was observed to be equivocal amongst the two groups. Statistically significant difference was observed in serum CRP value, Lichtenstein repair group having a higher value. Both open and endoscopic surgical techniques incite a systemic inflammatory response in the body. Lichtenstein repair had a higher serum CRP value compared to total extraperitoneal repair (TEP). However, it cannot be conclusively stated that TEP is associated with lesser SIR compared to the Lichtenstein repair on the basis of this study.

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Authors and Affiliations

  1. Department of General Surgery, Government Medical College & Hospital, Sec -32, Chandigarh, India

    Sudeep Singh, Navdeep Garg, Mandeep Singh, Rajesh Kumar Bansiwal & Rajeev Sharma

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  1. Sudeep Singh
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  2. Navdeep Garg
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  3. Mandeep Singh
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  4. Rajesh Kumar Bansiwal
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  5. Rajeev Sharma
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Correspondence to Navdeep Garg.

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Singh, S., Garg, N., Singh, M. et al. Comparison of Systemic Inflammatory Response After Total Extraperitoneal Repair and Lichtenstein Repair of Inguinal Hernia. Indian J Surg (2022). https://doi.org/10.1007/s12262-021-03278-z

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