Skip to main content

Advertisement

Log in

Gastric Outlet Obstruction in a Breast Cancer Survivor: Evaluation and Treatment

  • Case Report
  • Published:
Indian Journal of Surgery Aims and scope Submit manuscript

Abstract

Breast cancer patients need to be on regular follow-up after definitive treatment, for early detection and treatment of recurrence or distant metastasis. Gastrointestinal and peritoneal metastases from breast cancer are rare. Invasive lobular carcinoma has a tendency to spread to the gastrointestinal organs, and usually, is present a few years after the primary breast cancer has been treated. Histopathological examination with immunohistochemistry (IHC) analysis is paramount for diagnosis. We report a 49-year-old lady, treated for carcinoma breast 7 years back, on regular follow-up, who presented with features of gastric outlet obstruction. Endoscopic biopsy and detailed IHC from stomach was suggestive of metastases from breast carcinoma. Initial diagnostic and staging workup failed to detect peritoneal metastasis, however, which was confirmed by final histopathology from peritoneal biopsy. A high index of suspicion and accurate tissue diagnosis is imperative to plan the treatment in patients with a history of breast cancer with coexisting gastric symptoms. If a patient with solitary gastric metastasis is planned for curative surgical resection, it is very important to perform a staging laparoscopy and peritoneal biopsy to rule out metastasis to avoid unnecessary morbidity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

Data Availability

Not applicable.

References

  1. Cardoso F, Senkus E, Costa A, Papadopoulos E, Aapro M, André F, Harbeck N, Aguilar Lopez B, Barrios CH, Bergh J, Biganzoli L, Boers-Doets CB, Cardoso MJ, Carey LA, Cortés J, Curigliano G, Diéras V, el Saghir NS, Eniu A, Fallowfield L, Francis PA, Gelmon K, Johnston SRD, Kaufman B, Koppikar S, Krop IE, Mayer M, Nakigudde G, Offersen BV, Ohno S, Pagani O, Paluch-Shimon S, Penault-Llorca F, Prat A, Rugo HS, Sledge GW, Spence D, Thomssen C, Vorobiof DA, Xu B, Norton L, Winer EP (2018) 4th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 4). Ann Oncol 29(8):1634–1657

    Article  CAS  Google Scholar 

  2. Xiao W, Zheng S, Yang A, Zhang X, Zou Y, Tang H, Xie X (2018) Breast cancer subtypes and the risk of distant metastasis at initial diagnosis: a population-based study. Cancer Manag Res 10:5329–5338

    Article  CAS  Google Scholar 

  3. Orvieto E, Maiorano E, Bottiglieri L, Maisonneuve P, Rotmensz N, Galimberti V, Luini A, Brenelli F, Gatti G, Viale G (2008) Clinicopathologic characteristics of invasive lobular carcinoma of the breast: results of an analysis of 530 cases from a single institution. Cancer 113(7):1511–1520

    Article  Google Scholar 

  4. Ferlicot S, Vincent-Salomon A, Médioni J, Genin P, Rosty C, Sigal-Zafrani B, Fréneaux P, Jouve M, Thiery JP, Sastre-Garau X (2004) Wide metastatic spreading in infiltrating lobular carcinoma of the breast. Eur J Cancer 40(3):336–341

    Article  CAS  Google Scholar 

  5. Switzer N, Lim A, Lillian D et al (2015) Case series of 21 patients with extrahepatic metastatic lobular breast carcinoma to the gastrointestinal tract. Cancer Treat Commun 3:37–43

    Article  Google Scholar 

  6. Schwarz RE, Klimstra DS, Turnbull AD (1998) Metastatic breast cancer masquerading as gastrointestinal primary. Am J Gastroenterol 93(1):111–114

    Article  CAS  Google Scholar 

  7. Pectasides D, Psyrri A, Pliarchopoulou K, Floros T, Papaxoinis G, Skondra M, Papatsibas G, Macheras A, Athanasas G, Arapantoni-Datioti P, Economopoulos T (2009) Gastric metastases originating from breast cancer: report of 8 cases and review of the literature. Anticancer Res 29(11):4759–4763

    CAS  PubMed  Google Scholar 

  8. Namikawa T, Munekage E, Ogawa M, Oki T, Munekage M, Maeda H, Kitagawa H, Sugimoto T, Kobayashi M, Hanazaki K (2017) Clinical presentation and treatment of gastric metastasis from other malignancies of solid organs. Biomed Rep 7:159–162

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Naveena AN Kumar.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethics Approval

The institutional research committee has confirmed that no ethical approval is required.

Consent to Participate

Written informed consent was obtained from the patient.

Consent for Publication

Written informed consent for publication of their clinical details and images was obtained from the patient.

Code Availability

Not applicable.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yalla, P., J, P., Udupa, K.S. et al. Gastric Outlet Obstruction in a Breast Cancer Survivor: Evaluation and Treatment. Indian J Surg 83 (Suppl 2), 552–555 (2021). https://doi.org/10.1007/s12262-020-02611-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12262-020-02611-2

Keywords

Navigation