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Assessment of Risk Factors of Breast Cancer among Women Attending Tertiary Care Hospital of CHATTISGARH: a Case Control Study

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Abstract

Breast cancer is a multifactorial disease. This study was undertaken to study various risk factors associated with breast cancer. This was a case control study conducted between August 2017 to August 2018 at Department of surgery, Dr.B.R.A.M Hospital and Pt.JNM Medical college, Raipur, (C.G.). Cases were women with histopathologically confirmed breast cancer. Controls were age-matched women without any current breast problem or previous breast cancer. A total of 138 cases and 138 controls were enrolled. They were interviewed for menstrual history, breast feeding history, abortion history, family history etc. after obtaining informed written consent. The significant risk factors were age > 25 years at first child birth (OR 2.80, 95%CI 1.13–6.95), breast feeding history of <2 years (OR 2.88, 95%CI 1.09–7.6), history of abortion (OR 3.35, 95%CI 1.37–8.18) and co morbidities (OR 2.27, 95%CI 1.25–4.11). Age at first child birth >25 years, breast feeding duration of <2 years, history of abortion and comorbidities increases the risk of developing breast cancer.

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References

  1. Gajalakshmi CK, Shanta V (1991) Risk factors for female breast cancer. A hospital-based case-control study in Madras, India. Acta Oncol; 30:569–74. [PubMed]

  2. Mitrunen K, Hirvonen A (2003) Molecular epidemiology of sporadic breast cancer.The role of polymorphic genes involved in oestrogen biosynthesis and metabolism. Mutat Res 544(1):9–41

    Article  CAS  Google Scholar 

  3. Pakseresht S, Ingle G, Bahadur A, Ramteke VK, Singh MM, Garg S, Agarwal PN (2009) Risk factors with breast cancer among women in Delhi. Indian J Cancer 46(2):132–138. https://doi.org/10.4103/0019-509X.49151

    Article  CAS  PubMed  Google Scholar 

  4. Rao DN, Ganesh B, Desai PB (1994) Role of reproductive factors in breast cancer in a low-risk area: a case-control study. Br J Cancer 70(1):129–132

    Article  CAS  Google Scholar 

  5. Kuru B, Ozaslan C, Ozdemir P, Dinc S, Camlibel M, Alagol H (2002) Risk factors for breast cancer in Turkish women with early pregnancies and long-lasting lactation--a case-control study. Acta Oncol 41(6):556–561

    Article  Google Scholar 

  6. Gajalakshmi V,Mathew A, Brennan P,Rajan B, Kanimozi VC, Mathews A, et al. (2009) Breast feeding and breast cancer risk in India: A multicentric case control study.Int J Cancer. 125:662–5 [PubMed]

  7. McCredie M, Paul C, Skegg DC, Williams S (1998) Reproductive factors and breast cancer in New Zealand. Int J Cancer 76(2):182–188

    Article  CAS  Google Scholar 

  8. Indian J (2013) Cancer. 50(1):65–70. https://doi.org/10.4103/0019-509X.112307

    Article  Google Scholar 

  9. Lafta R, Qais E, Al Shatari S (2013) Risk Factors of Breast Cancer among Women (A Sample from Baghdad). Iraqi J. Comm. Med 1(1):1–6

    Google Scholar 

  10. Tulinius H, Sigvaldason H, Tryggvadóttir L (1999) Breast cancer incidence and familiality in Iceland during 75 years from 1921 to 1995.J med genet, 36:103-7. Google scholar

  11. Darweesh A(2009) Risk factors of breast Cancer among Palestinian women in North West Bank. Msc-thesis, Al-Najah National University, Nablus, Palestine

  12. Tavani A, Gallus S, La Vecchia C et al (1999) Risk factors for breast cancer in women under 40 years. Eur J Cancer 35(9):1361–1367

    Article  CAS  Google Scholar 

  13. Kaur N, Attam A, Saha S et al (2011) Breast Cancer risk factor profile in Indian women. JIMSA 24:163–165

    Google Scholar 

  14. Parameshwari P, Muthukumar K, Gladius JH (2013) A population based case control study on breast cancer and the associated risk factors in a rural setting in Kerala, Southern India J Clin Diagnostic Res;7(9):1913–1916. doi:https://doi.org/10.7860/JCDR/2013/5830.3356

  15. Matalqah L, Radaideh K, Yusoff ZM, Awaisu A (2011) Predictors of breast cancer among women in a northern state of Malaysia: a matched case-control study. Asian Pac J Cancer Prev 12(6):1549–1553

    PubMed  Google Scholar 

  16. Iwasaki M, Otani T, Inoue M, Sasazuki S, Tsugane S (2007) Role and impact of menstrual and reproductive factors on breast cancer risk in Japan. Eur J Cancer Prev 16(2):116–123. https://doi.org/10.1097/01.cej.0000228410.14095.2d

    Article  PubMed  Google Scholar 

  17. Shantakumar S, Terry MB, Teitelbaum SL, Britton JA, Millikan RC, Moorman PG, Neugut AI, Gammon MD (2007) Reproductive factors and breast cancer risk among older women. Breast Cancer Res Treat 102(3):365–374. https://doi.org/10.1007/s10549-006-9343-4

    Article  PubMed  Google Scholar 

  18. Larsson SC, Mantzoros CS, Wolk A (2007) Diabetes mellitus and risk of breast cancer: a meta- analysis. Int J Cancer 121:856–862

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department Of Surgery, Pt. Jawaharlal Nehru Memorial Medical College & Dr. Bhim Rao Ambedkar Memorial Hospital, Raipur, India

    Manju Singh, Amit Agrawal & Niranjan H. R

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  1. Manju Singh
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  2. Amit Agrawal
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  3. Niranjan H. R
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Correspondence to Amit Agrawal or Niranjan H. R.

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This study was approved by the Institutional Ethical committee.

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Singh, M., Agrawal, A. & H. R, N. Assessment of Risk Factors of Breast Cancer among Women Attending Tertiary Care Hospital of CHATTISGARH: a Case Control Study. Indian J Surg 83 (Suppl 2), 359–363 (2021). https://doi.org/10.1007/s12262-019-02034-8

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