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Specific and Selective Bacteriophages in the Fight against Multidrug-resistant Acinetobacter baumannii

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Virologica Sinica

Abstract

Acinetobacter baumannii causes serious infections especially in immunocompromised and/or hospitalized patients. Several A. baumannii strains are multidrug resistant and infect wounds, bones, and the respiratory tract. Current studies are focused on finding new effective agents against A. baumannii. Phage therapy is a promising means to fight this bacterium and many studies on procuring and applying new phages against A. baumannii are currently being conducted. As shown in animal models, phages against multidrug-resistant A. baumannii may control bacterial infections caused by this pathogen and may be a real hope to solve this dangerous health problem.

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Acknowledgements

This work was supported by the statutory funds from the Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences. The authors also thank to Norbert Łodej for making figure to this paper.

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Authors and Affiliations

  1. Bacteriophage Laboratory, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114, Wrocław, Poland

    Natalia Bagińska, Anna Pichlak, Andrzej Górski & Ewa Jończyk-Matysiak

  2. Phage Therapy Unit, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114, Wrocław, Poland

    Andrzej Górski

  3. Department of Clinical Immunology, Transplantation Institute, Medical University of Warsaw, 53-114, Warsaw, Poland

    Andrzej Górski

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  1. Natalia Bagińska
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Correspondence to Ewa Jończyk-Matysiak.

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Andrzej Górski, is co-inventor of patents owned by the Institute and covering phage preparations. Other authors declare that they have no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Bagińska, N., Pichlak, A., Górski, A. et al. Specific and Selective Bacteriophages in the Fight against Multidrug-resistant Acinetobacter baumannii. Virol. Sin. 34, 347–357 (2019). https://doi.org/10.1007/s12250-019-00125-0

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