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The relationship between childhood trauma, early-life stress, and alcohol and drug use, abuse, and addiction: An integrative review

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Abstract

In this review, we discuss the relationship between childhood trauma, early-life stress, and substance use, abuse, and addiction. We further provide theories and neural studies to explain this relationship as well as potential treatment strategies for alcohol and drug abuse and addiction based on understanding types of early-life stressors that lead to both drug use and relapse.

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Correspondence to Ahmed A. Moustafa.

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The authors have not received any funds related to this study and do not have any conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Moustafa, A.A., Parkes, D., Fitzgerald, L. et al. The relationship between childhood trauma, early-life stress, and alcohol and drug use, abuse, and addiction: An integrative review. Curr Psychol 40, 579–584 (2021). https://doi.org/10.1007/s12144-018-9973-9

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  • DOI: https://doi.org/10.1007/s12144-018-9973-9

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