Abstract
Desmoid-type fibromatosis rarely occurs in the oral tongue. Diagnostic imaging, including ultrasound, is useful for delineating the extent of the lesion and can aid in treatment planning. However, definitive diagnosis is made based on the characteristic histologic features, which include cytologically bland spindle cells with surrounding collagenous matrix and minimal mitotic activity. Immunohistochemical analysis of these lesions reveals that they are classically positive, at least focally, for smooth muscle actin, calponin and muscle-specific actin. These features are exemplified in this sine qua non radiology-pathology correlation article.
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Aydil U, Kizil Y. Tongue ultrasonography in the diagnosis of a submucosal tongue infection mimicking a neoplasm: a case report. Gazi Med J. 2012;23:65–8.
de Fatima Correia-Silva J, Duarte E, Lacerda J, de Sousa S, Mesquita R, Gomez R. Alveolar soft part sarcoma of the tongue. Oral Oncol Extra. 2006;42:241–3.
Leroy X, Delobelle A, Lefebvre J, Cabaret V, Bloget F, Vilain M. Epithelioid sarcoma of the tongue. J Clin Pathol. 1997;50:869–70.
McDonald E, Yi E, Wenger D. Best cases from the AFIP: extraabdominal desmoid-type fibromatosis. Radiographics. 2008;28:901–6.
Wong S. Diagnosis and management of desmoid tumors and fibrosarcoma. J Surg Oncol. 2008;97:554–8.
Ferenc T, Sygut J, Kopczynski J, Mayer M, Latos-Bielenska A, Dziki A, Kulig A. Aggressive fibromatosis (desmoid tumors): definition, occurrence, pathology, diagnostic problems, clinical behavior, genetic background. Pol J Pathol. 2006;57:5–15.
Gonzales-Garci R, Escorial-Hernandez V, Munoz-Guerra M, Rodriguez-Campo F, Reina-Duran T, Nieto-Llanos S, Naval-Gias L. Fibromatosis of the tongue: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:E31–4.
Hoos A, Lewis J, Urist M, Shaha A, Hawkins W, Shah J, Brennan M. Desmoid tumors of the head and neck—a clinical study of a rare entity. Head Neck. 2000;22:814–21.
Horn C, Thaker H, Tampakopoulou D, de Serres L, Keller J, Haddad J Jr. Tongue lesions in the pediatric population. Otolaryngol Head Neck Surg. 2001;124:164–9.
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Al-Saraf, A., Yassan, L., Cipriani, N.A. et al. Desmoid-Type Fibromatosis of the Tongue. Head and Neck Pathol 10, 527–529 (2016). https://doi.org/10.1007/s12105-016-0716-7
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DOI: https://doi.org/10.1007/s12105-016-0716-7