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Percutaneous recanalization for hepatic vein-type Budd-Chiari syndrome: long-term patency and survival

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Abstract

Objective

To determine the long-term patency and survival of percutaneous recanalization for hepatic vein (HV)-type Budd-Chiari syndrome (BCS).

Methods

From March 2009 to November 2014, consecutive symptomatic HV-type BCS patients were treated by percutaneous recanalization in our centers. These patients underwent main HV (MHV) or accessory HV (AHV) recanalization. Data on patient characteristics, technical success, clinical success, long-term patency, and survival were collected and analyzed.

Results

During the enrolled periods, a total of 143 symptomatic HV-type BCS patients were treated by percutaneous recanalization in our centers. Technical success was achieved in 140 of 143 patients. One hundred eleven patients underwent MHV recanalization, and 29 underwent AHV recanalization. Clinical success was achieved in 136 of 140 patients. The mean MHV/AHV pressure decreased from 33.5 ± 4.1 mmHg before treatment to 12.5 ± 3.1 mmHg after treatment (p = 0.000). The 136 patients were followed for 7–75 months (mean 33.9 ± 15.3 months). Twenty-eight patients experienced re-obstruction of MHV (n = 24) or AHV (n = 4) at 3 to 36 months (mean 18.0 ± 11.5 months) after treatment. The cumulative 1-, 3-, and 6-year primary patency rates were 91.1, 77.4, and 74.0 %, respectively. The cumulative 1-, 3-, and 6-year secondary patency rates were 97.0, 92.4, and 88.8 %, respectively. The cumulative 1-, 3-, and 6-year survival rates were 97.7, 92.2, and 90.0 %, respectively.

Conclusion

Percutaneous recanalization can provide good long-term patency and survival in HV-type BCS patients.

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Author notes

    Authors and Affiliations

    1. Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical College, 99 West Huai-hai Road, Xuzhou, 221006, China

      Yan-Feng Cui & Hao Xu

    2. Department of Radiology, Xuzhou Central Hospital, 199 South Jie-fang Road, Xuzhou, 221009, China

      Yu-Fei Fu & De-Chun Li

    Authors
    1. Yan-Feng Cui
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    2. Yu-Fei Fu
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    3. De-Chun Li
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    4. Hao Xu
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    Corresponding author

    Correspondence to Hao Xu.

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    Conflicts of interest

    Yan-Feng Cui, Yu-Fei Fu, De-Chun Li, and Hao Xu declare that they have no conflict of interest.

    Ethical approval

    All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required. This article does not contain any studies with animals performed by any of the authors. This was a retrospective study approved by our Institutional Review Board. Each patient received the details about percutaneous recanalization and provided written informed consent for percutaneous recanalization before treatment.

    Informed consent

    Informed consent was obtained from all individual participants included in the study.

    Additional information

    Y.-F. Cui and Y.-F. Fu contributed equally to this work.

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    Cui, YF., Fu, YF., Li, DC. et al. Percutaneous recanalization for hepatic vein-type Budd-Chiari syndrome: long-term patency and survival. Hepatol Int 10, 363–369 (2016). https://doi.org/10.1007/s12072-015-9676-3

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    • DOI: https://doi.org/10.1007/s12072-015-9676-3

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