Abstract
Pseudolymphoma is a reactive process involving lymphadenopathy, polyclonal proliferation of B or T-cells, simulating oral lymphoma. With its incidence being very rare, only four cases have been reported in oral cavity with the detailed immunocytochemical examination, which can be due to this entity's unawareness, underdiagnosis or overdiagnosis. It is prerogative to perform immunocytochemical investigations to prevent overdiagnosis as lymphoma, which can be debilitating to the patient. Wherein the treatment of pseudolymphoma initially includes topical or intralesional corticosteroid, antibiotics to surgical and radiotherapy based on its etiology. Herein, we discuss B-cell follicular lymphoid hyperplasia previously diagnosed as small round cell tumor.
Similar content being viewed by others
References
Tian Z, Shiyu Z, Tao W, Li L, Yuehua L, Hongzhong J (2019) Lymphoma or pseudolymphoma: a report of six cases and review of the literature. Dermatol Ther 32(4):e12807
Mitteldorf C, Kempf W (2020) Cutaneous pseudolymphoma—A review on the spectrum and a proposal for a new classification. J Cutan Pathol 47(1):76–97
Kabani S, Cataldo E, Folkerth R, Delellis RA, Bhan I, Farren P, Neville T (1988) Atypical lymphohistiocytic infiltrate (pseudolymphoma) of the oral cavity. Oral Surg Oral Med Oral Pathol 66(5):587–592
Río ED, Yus ES, Requena L, Puente LG, Veiga HV (1997) Oral pseudolymphoma: a report of two cases. J Cutan Pathol 24(1):51–55
Ferrisse TM, de Oliveira AB, Grifoni LD, da Silveira HA, Bagatini AT, Bufalino A, León JE (2020) Oral pseudolymphoma: a diagnostic challenge. Oral Surg Oral Med Oral Pathol Oral Radiol 129(1):e23
Miguel D, Peckruhn M, Elsner P (2018) Treatment of cutaneous pseudolymphoma: a systematic review. Acta Derm Venereol 98(3):310–317
Ruckley RW, Gordon D, Conroy B (1984) Pseudolymphoma of the tongue mimicking Hodgkin’disease (A Case Report). J Laryngol Otol 98(7):73741
Bergman R (2010) Pseudolymphoma and cutaneous lymphoma: facts and controversies. Clin Dermatol 28(5):568–574
Funding
None.
Author information
Authors and Affiliations
Contributions
All the authors contributed significantly to this manuscript.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no known conflict of interest.
Consent for Publication
Not applicable.
Ethical Approval
Not applicable.
Consent to Participate
Not applicable.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Selvam, R., John, S., Sankar, R. et al. B-cell Follicular Lymphoid Hyperplasia (Pseudolymphoma) of the Oral Cavity: A Diagnostic Quandary. Indian J Otolaryngol Head Neck Surg 76, 1029–1032 (2024). https://doi.org/10.1007/s12070-023-04086-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-023-04086-5