Abstract
Extraosseous osteosarcoma is a rare malignant soft tissue neoplasm, and extraosseous osteosarcoma of the parotid gland is very rare. It has a very aggressive course, and there are no standardized treatment guidelines. We report the case of a 20 year old male patient who presented with history of right neck swelling since 6 years for which he had undergone right parotid surgery 5 years ago. The final histopathological report indicated that the mass was a pleomorphic adenoma. One year after the first surgery, the patient experienced recurrence of swelling over the operated site, and the size of the swelling has been increasing gradually since then. He was evaluated clinically, and a large mass was noted over the upper aspect of the right upper neck, extending to the occipital and parotid regions. An MRI scan was done which showed a 12 × 10 × 8 cm lesion centred in the right parotid gland, involving paraspinal muscles, C1–C2 vertebrae and extending into the parapharyngeal space. FNAC of the lesion showed features of pleomorphic adenoma. The patient underwent a complete excision of the tumour. The patient’s post-operative period was uneventful. The final histopathological report of the patient was extraosseous osteosarcoma of the parotid gland. The patient was referred for adjuvant radiotherapy. He has been on regular follow-up for the past 6 months and has shown no sign of recurrence. EOS is an extremely rare tumour of the head and neck region which often requires extensive surgical resection with or without adjuvant radiotherapy. It has a high rate of local recurrence and a very low disease free survival. Such patients should be kept on a close follow-up.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Data Availability
All material submitted in the article are original.
References
Clark L, Unni KK, Dahlin DC (1983) Osteosarcoma of the jaw. Cancer 51:2311
Luna-Ortiz K, Ortega-Gutierrez C, Dominguez-Malagon H et al (2012) Extraosseous osteosarcoma in the neck. Auris Nasus Larynx 39:333
Manning JT, Raymond AK, Batsakis JG (1986) Extraosseous osteogenic sarcoma of the parotid gland. J Laryngol Otol 100(2):239–242
Hatano H, Morita T, Kobayashi H et al (2005) Extraskeletal osteosarcoma of the jaw. Skeletal Radiol 34:171
Saito Y, Miyajima C, Nakao K et al (2008) Highly malignant submandibular extraskeletal osteosarcoma in a young patient. Auris Nasus Larynx 35:576
Stimson PG, Valenzuela-Espinoza A, Tortoledo ME et al (1989) Primary osteosarcoma of the parotid gland. Oral Surg Oral Med Oral Pathol 68:80
Kosec A, Vucic M, Bedekovic V, Ivkic M (2016) Osteoblastic Extraosseous Osteosarcoma of the Neck. J Oral Maxillofac Surg 75(3):e1-1.e5
Adeyemo A, Ameye SA (2016) A rare case of extraosseous osteosarcoma of parotid gland. East Central Afr J Surg 21(2):100–105
Huang EC, Ghazikhanian V, Qian X (2016) Giant cell-rich osteosarcoma of the parotid gland: an exceptionally rare entity at an unusual site. Diagn Cytopathol 44(12):1107–1111
Hamamoto T, Kono T, Furuie H et al (2018) Extraskeletal osteosarcoma in the parotid gland: a case report. Auris Nasus Larynx 45(3):644–647
Ge X, Wang M, Zhai X, (2022) Extraskeletal Osteosarcoma in the parotid gland a case report and review of literature. Eur J Med Res, DOI: 10.21203/rs.3.rs-1511384/v2
Zhang JS, Wen G, Liu Y, Wu ZH, Chen GD, Wang H, Zhou TC (2018) Extraskeletal osteosarcoma in right neck subcutaneous tissue: A case report of an extremely rare tumour. Mol Clin Oncol 9(2):149–154
Aslan M, Samdanci ET (2022) A very rare mass mimicking paraganglioma in the parapharyngeal area: extraskeletal osteosarcoma. Braz J Otorhinolaryngol 88:279–282
Nicol KK, Ward WG, Savage PD et al (1998) Fine-needle aspiration biopsy of skeletal versus extraskeletal osteosarcoma. Cancer 84:176
Bane BL, Evans HL, Ro JY et al (1990) Extraskeletal osteosarcoma. a clinic-pathologic review of 26 cases. Cancer 65:2762
Ahmad SA, Patel SR, Ballo MT et al (2002) Extraosseous osteosarcoma: response to treatment and long-term outcome. J Clin Oncol 20:521
Edge SB, Byrd DR, Compton CC et al (2010) AJCC Cancer Staging Manual. Springer, New York
Longhi A, Bielack SS, Grimer R et al (2017) Extraskeletal osteosarcoma: a European musculoskeletal oncology society study on 266 patients. Eur J Cancer 74:9–16
Acknowledgements
I would like to acknowledge the efforts of the department of robotics and surgical oncology, department of radiology and pathology of BLK—MAX Superspeciality hospital.
Funding
None.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
No potential conflict of interest relevant to this article exist.
Informed Consent
Written and informed consent has been taken from the patient for the procedure and all procedures have been done ethically.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Dabas, S.K., Menon, N.N., Ranjan, R. et al. A Rare Case of Extraosseous Osteosarcoma (EOS) of Parotid Gland. Indian J Otolaryngol Head Neck Surg 75, 1215–1220 (2023). https://doi.org/10.1007/s12070-023-03497-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-023-03497-8