Skip to main content

Advertisement

Log in

Sinonasal and Infratemporal Schwannoma: Rare Case Report with Literature Review

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Abstract

Schwann cells are responsible for the production of the myelin sheath around the axons of the peripheral nervous system. Benign neoplasms which originate from Schwann cells are hence termed Schwannomas or Neurilemmomas. They present as slow-growing, solitary, encapsulated, benign masses usually in association with nerve trunks. Schwannomas are relatively rare tumors with 25–45% occurring in the head and neck region. These case reports aim to describe the presentations, work-up, and treatment of two patients with head and neck schwannoma in atypical locations. Both patients had a history of gradually increasing swelling, the first originating from the sino-nasal region and the second from the temporal/ infratemporal region. Complete surgical excision of the tumor was done in both cases with no reported recurrence at 18 months follow-up. The final diagnosis was made based on histopathology and immunohistochemistry findings. Schwannomas often present a diagnostic dilemma and should be considered a possibility in all head and neck tumors. Recurrence is rare.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14
Fig. 15

Similar content being viewed by others

References

  1. Bansal R, Trivedi P, Patel S (2005) Schwannoma of the tongue. Oral Oncol Extra 41(2):15–17

    Article  Google Scholar 

  2. Chiofalo M, Longo F, Marone U, Franco R, Petrillo A, Pezzullo L (2009) Cervical vagal schwannoma. a case report. Acta Otorhinolaryngol Ital 29(1):33

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Verma A, Banerjee K, Verma A, Singh S, Rao J, Om P (2013) Maxillary neurilemmoma—Rarest of the rare tumor: report of 2 cases. Int J Surg Case Rep 4(11):1044–1047

    Article  PubMed  PubMed Central  Google Scholar 

  4. Kang GC, Soo K-C, Lim DT (2007) Extracranial non-vestibular head and neck schwannomas: a ten-year experience. Ann-Acad Med Singapore 36(4):233

    Article  PubMed  Google Scholar 

  5. Diaz DD, Kennedy KS, Parker GS, White VJ (1991) Schwannoma of the submandibular gland. Head Neck 13(3):239–242

    Article  CAS  PubMed  Google Scholar 

  6. Piscioli F, Antolini M, Pusiol T, Dalrì P, Bello DL, Mair K (1986) Malignant schwannoma of the submandibular gland. ORL 48(3):156–161

    Article  CAS  PubMed  Google Scholar 

  7. Vijendra SS, Rao RA, Prasad V, Haseena S, Niprupama M (2015) A giant vagal schwannoma with unusual extension from skull base to the mediastinum. J Cancer Res Ther 11(4):970

    Article  CAS  PubMed  Google Scholar 

  8. Shrikrishna B, Jyothi A, Kulkarni N, Mazhar M (2016) Extracranial head and neck schwannomas: our experience. Indian J Otolaryngol Head Neck Surg 68(2):241–247

    Article  CAS  PubMed  Google Scholar 

  9. Awasthi S, Dutta A (2011) Cervical sympathetic chain schwannoma: a case report. Indian J Otolaryngol Head Neck Surg 63(3):292–294

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Batsakis JG, Sneige N (1989) Parapharyngeal and retropharyngeal space diseases. Ann Otol, Rhinol Laryngol 98(4):320–321

    Article  CAS  PubMed  Google Scholar 

  11. Leu Y, Chang K (2002) Extracranial head and neck schwannomas: a review of 8 years experience. Acta Otolaryngol 122(4):435–437

    Article  CAS  PubMed  Google Scholar 

  12. Muranjan S, Jagasia V, Pusalkar A (2001) Schwannoma of the cheek. Indian J Otolaryngol Head Neck Surg 53(2):140

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Calcaterra TC, Rich JR, Ward PW (1974) Neurilemoma of the sphenoid sinus. Arch Otolaryngol 100(5):383–385

    Article  CAS  PubMed  Google Scholar 

  14. Ahad A (1997) Schwannoma of submandibular region. Indian J Otolaryngol Head Neck Surg 49(4):341–343

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Rajan R, Rajan R (1994) Tumours of the parapharyngeal space: Our experience. Indian J Otolaryngol Head Neck Surg 46(2):88–91

    Article  Google Scholar 

  16. Padasali PS, Shankaregowda V, Kshirsagar SD (2015) Median nerve schwannoma: a case and review of literature. Asian J Neurosurg 10(3):212

    Article  PubMed  PubMed Central  Google Scholar 

  17. Hilton DA, Hanemann CO (2014) Schwannomas and their pathogenesis. Brain Pathol 24(3):205–220

    Article  PubMed  PubMed Central  Google Scholar 

  18. Ganju A, Roosen N, Kline DG, Tiel RL (2001) Outcomes in a consecutive series of 111 surgically treated plexal tumors: a review of the experience at the Louisiana State University Health Sciences Center. J Neurosurg 95(1):51–60

    Article  CAS  PubMed  Google Scholar 

  19. Anil G, Tan T (2010) Imaging characteristics of schwannoma of the cervical sympathetic chain: a review of 12 cases. Am J Neuroradiol 31(8):1408–1412

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Kakkar C, Shetty CM, Koteshwara P, Bajpai S (2015) Telltale signs of peripheral neurogenic tumors on magnetic resonance imaging. Indian J Radiol Imag 25(04):453–458

    Article  Google Scholar 

  21. Hirano S (1994) Extracranial neurinomas of head and neck. Practica Otologica Kyoto 87:253–257

    Article  Google Scholar 

  22. Iacconi P, Faggioni M, De Bartolomeis C, Iacconi C, Caldarelli C (2012) Cervical sympathetic chain schwannoma: a case report. Acta Otorhinolaryngol Ital 32(2):133

    CAS  PubMed  PubMed Central  Google Scholar 

  23. Ziadi A, Saliba I (2010) Malignant peripheral nerve sheath tumor of intracranial nerve: a case series review. Auris Nasus Larynx 37(5):539–545

    Article  PubMed  Google Scholar 

  24. Valeyrie-Allanore L, Ismaili N, Bastuji-Garin S, Zeller J, Wechsler J, Revuz J et al (2005) Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis 1. Br J Dermatol 153(1):79–82

    Article  CAS  PubMed  Google Scholar 

  25. Murley R (1948) A case of neurinoma of the vagus nerve in the neck. J Br Surg 36(141):101–103

    Article  CAS  Google Scholar 

  26. Callum E (1949) Neurinoma of cervical sympathetic chain. J Br Surg 37(145):117

    Article  CAS  Google Scholar 

  27. Skolnik AD, Loevner LA, Sampathu DM, Newman JG, Lee JY, Bagley LJ et al (2016) Cranial nerve schwannomas: diagnostic imaging approach. Radiographics 36(5):1463–1477

    Article  PubMed  Google Scholar 

  28. Liu H-L, Yu S-Y, Li GK-H, Wei WI (2011) Extracranial head and neck schwannomas: a study of the nerve of origin. Eur Arch Oto-Rhino-Laryngol 268(9):1343–1347

    Article  Google Scholar 

  29. Yasumatsu R, Nakashima T, Miyazaki R, Segawa Y, Komune S (2013) Diagnosis and management of extracranial head and neck schwannomas: a review of 27 cases. Int J Otolaryngol. https://doi.org/10.1155/2013/973045

    Article  PubMed  PubMed Central  Google Scholar 

  30. Valentino J, Boggess MA, Ellis JL, Hester TO, Jones RO (1998) Expected neurologic outcomes for surgical treatment of cervical neurilemomas. Laryngoscope 108(7):1009–1013

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aamir Malick Saifi.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Yes.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Saifi, A.M., Kapoor, P., Bajaj, A. et al. Sinonasal and Infratemporal Schwannoma: Rare Case Report with Literature Review. Indian J Otolaryngol Head Neck Surg 75 (Suppl 1), 234–241 (2023). https://doi.org/10.1007/s12070-022-03424-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-022-03424-3

Keywords

Navigation