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Diagnostic and Management Guidelines of Thyroid Tuberculosis: Our Experience and Systematic Review

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Objective

Thyroid tuberculosis has non-specific clinical presentation, difficult diagnosis and specific medical management. The aim of this article is to present and share a review of the English-language literature on thyroid tuberculosis in order to gain a better understanding of diagnostic methods and provide guidelines for its management and to present our experience of three cases.

Methods

The systematic search of the literature was performed on Pubmed and Medline from 1950 to 2019 according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement.

Results

We retrieved 13 manuscripts meeting our criteria from the search. There were 7 case series, and 6 manuscripts with review of the literature.

Conclusion

Direct histopathological demonstration is the best diagnostic modality. FNAC is the study of choice and PCR assay increases its sensitivity. The standard short course ATT for 6 months is recommended for isolated thyroid TB and for widespread disease, 12 months therapy is recommended. Surgery is reserved for failure of medical therapy and abscess formation.

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Funding

The authors did not receive any funding for this article.

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Authors and Affiliations

  1. Department of General Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hopital, New Delhi, India

    Poras Chaudhary, Utsav Bhadana, Anish Anand & Neeti Kapur

Authors
  1. Poras Chaudhary
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  2. Utsav Bhadana
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  3. Anish Anand
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  4. Neeti Kapur
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Contributions

Poras chaudhary: study design, concept, literature search, data analysis, drafting. Utsav Bhadana: Drafting, data analysis. Anish Anand: drafting, literature search. Neeti Kapur: critical analysis.

Corresponding author

Correspondence to Neeti Kapur.

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The authors have no conflicts of interest to declare that are relevant to the content of this article.

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This is a systematic review. The Institution Research Ethics Committee has confirmed that no ethical approval is required.

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Chaudhary, P., Bhadana, U., Anand, A. et al. Diagnostic and Management Guidelines of Thyroid Tuberculosis: Our Experience and Systematic Review. Indian J Otolaryngol Head Neck Surg 75, 1302–1310 (2023). https://doi.org/10.1007/s12070-022-03275-y

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  • DOI: https://doi.org/10.1007/s12070-022-03275-y

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