Skip to main content
Log in

Results of 301 Parotidectomies: A Twenty-Year Experience of One Single Institution

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

To evaluate demographic, clinical, surgical and histopathological results and complications of 301 parotidectomies performed in southern part of Turkey. The results of 297 patients undergoing 301 parotidectomies between 2000 and 2019 were retrospectively reviewed. Four patients underwent bilateral parotidectomy. Age, gender, side and size of lesion, postoperative facial nerve function (FNF) for benign tumors and types of surgery were evaluated. There were 172 male and 125 female patients. The mean age was 52.53 ± 16.67 years (range 11–90 years). Patients with malignant tumor had higher mean age than the patients with benign diseases (p < 0.001) and the mean age of Warthin tumor (WT) patients was significantly higher than pleomorphic adenoma (PA) (p < 0.001). There was a significant male dominancy in WTs than the PAs (p < 0.001). The mean size of the malignant tumors was significantly higher than the benign tumors (p = 0.012). The mean of cigarette smoking value (pack/year) was higher in WTs than the PAs (p < 0.001). WT incidence was slightly higher than PA in between years 2010 and 2019 (p = 0.272) compared to between years 2000 and 2009. Fine needle aspiration biopsy had a sensitivity of 96% and specificity of 78% for the benign tumors. Tumor location (p < 0.001) and tumor size (p = 0.034) had negative effect on the postoperative FNF. The incidence of WT had a significant rise in the last decade. Deep lobe tumors and increased tumor size had effect postoperative FNF. Experience of surgeon is more important than nerve monitoring to prevent facial paralysis. Partial superficial parotidectomy was available methods for small benign tumors in tail of the parotid gland.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

Availability of Data and Materials

Not applicable.

Code Availability

Not applicable.

References

  1. Kara T, Arpacı RB, Vayısoğlu Y, Serinsöz E, Gürsoy D, Özgür A et al (2017) Hydatid cyst of parotid gland: an unusual case diagnosed by fine needle aspiration biopsy. Turk Patoloji Derg 33:171–174. https://doi.org/10.5146/tjpath.2014.01265

    Article  PubMed  Google Scholar 

  2. Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8:177–184. https://doi.org/10.1002/hed.2890080309

    Article  CAS  PubMed  Google Scholar 

  3. Bradley PJ, McGurk M (2013) Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg 51:399–403. https://doi.org/10.1016/j.bjoms.2012.10.002

    Article  PubMed  Google Scholar 

  4. Psychogios G, Vlastos I, Thölken R, Zenk J (2020) Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany. Eur Arch Otorhinolaryngol 277:2081–2084. https://doi.org/10.1007/s00405-020-05894-z

    Article  PubMed  Google Scholar 

  5. Franzen AM, Kaup Franzen C, Guenzel T, Lieder A (2018) Increased incidence of Warthin tumours of the parotid gland: a 42-year evaluation. Eur Arch Otorhinolaryngol 275:2593–2598. https://doi.org/10.1007/s00405-018-5092-3

    Article  PubMed  Google Scholar 

  6. Zhan KY, Khaja SF, Flack AB, Day TA (2016) Benign parotid tumors. Otolaryngol Clin N Am 49:327–342. https://doi.org/10.1016/j.otc.2015.10.005

    Article  Google Scholar 

  7. Liu CC, Jethwa AR, Khariwala SS, Johnson J, Shin JJ (2016) Sensitivity, specificity, and posttest probability of parotid fine-needle aspiration: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 154:9–23. https://doi.org/10.1177/0194599815607841

    Article  PubMed  Google Scholar 

  8. Feinstein AJ, Alonso J, Yang SE, St John M (2016) Diagnostic Accuracy of fine-needle aspiration for parotid and submandibular gland lesions. Otolaryngol Head Neck Surg 155:431–436. https://doi.org/10.1177/0194599816643041

    Article  PubMed  Google Scholar 

  9. Schmidt RL, Hall BJ, Wilson AR, Layfield LJ (2011) A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions. Am J Clin Pathol 136:45–59. https://doi.org/10.1309/ajcpoie0cznat6sq

    Article  PubMed  Google Scholar 

  10. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (2017) WHO classification of head and neck tumours. In: El-Naggar AK (ed) World Health Organization classification of tumours, 4th edn. International Agency for Research on Cancer (IARC), Lyon, pp 159–201

    Google Scholar 

  11. Patel DK, Morton RP (2016) Demographics of benign parotid tumours: Warthin’s tumour versus other benign salivary tumours. Acta Otolaryngol 136:83–86. https://doi.org/10.3109/00016489.2015.1081276

    Article  PubMed  Google Scholar 

  12. Zbären P, Schüpbach J, Nuyens M, Stauffer E, Greiner R, Häusler R (2003) Carcinoma of the parotid gland. Am J Surg 186:57–62. https://doi.org/10.1016/s0002-9610(03)00105-3

    Article  PubMed  Google Scholar 

  13. Reinheimer A, Vieira DS, Cordeiro MM, Rivero ER (2019) Retrospective study of 124 cases of salivary gland tumors and literature review. J Clin Exp Dent 11(11):e1025-32. https://doi.org/10.4317/jced.55685

    Article  Google Scholar 

  14. Tian Z, Li L, Wang L, Hu Y, Li J (2010) Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg 39:235–242. https://doi.org/10.1016/j.ijom.2009.10.016

    Article  CAS  PubMed  Google Scholar 

  15. Spitz MR, Fueger JJ, Goepfert H, Newell GR (1990) Salivary gland cancer. A case-control investigation of risk factors. Arch Otolaryngol Head Neck Surg 116:1163–1166. https://doi.org/10.1001/archotol.1990.01870100057012

    Article  CAS  PubMed  Google Scholar 

  16. Spiro RH, Armstrong J, Harrison L, Geller NL, Lin SY, Strong EW (1989) Carcinoma of major salivary glands. Recent trends. Arch Otolaryngol Head Neck Surg 115:316–321. https://doi.org/10.1001/archotol.1989.01860270058015

    Article  CAS  PubMed  Google Scholar 

  17. Yoo GH, Eisele DW, Askin FB, Driben JS, Johns ME (1994) Warthin’s tumor: a 40-year experience at The Johns Hopkins Hospital. Laryngoscope 104:799–03. https://doi.org/10.1288/00005537-199407000-00004

    Article  CAS  PubMed  Google Scholar 

  18. Eytan DF, Yin LX, Maleki Z, Koch WM, Tufano RP, Eisele DW et al (2018) Utility of preoperative fine needle aspiration in parotid lesions. Laryngoscope 128:398–402. https://doi.org/10.1002/lary.26776

    Article  PubMed  Google Scholar 

  19. Ciuman RR, Oels W, Jaussi R, Dost P (2012) Outcome, general, and symptom-specific quality of life after various types of parotid resection. Laryngoscope 122:1254–1261. https://doi.org/10.1002/lary.23318

    Article  PubMed  Google Scholar 

  20. Lee SK, Rho BH, Won KS (2018) Parotid incidentaloma identified by combined 18F-fluorodeoxyglucose whole-body positron emission tomography and computed tomography: findings at grayscale and power Doppler ultrasonography and ultrasound-guided fine-needle aspiration biopsy or core-needle biopsy. Eur Radiol 28:2856–2869. https://doi.org/10.1007/s00330-017-5247-4

    Article  Google Scholar 

  21. Wang HC, Zuo CT, Hua FC, Huang ZM, Tan HB, Zhao J et al (2010) Efficacy of conventional whole-body 18F-FDG PET/CT in the incidental findings of parotid masses. Ann Nucl Med 24:571–577. https://doi.org/10.1007/s12149-010-0394-6

    Article  PubMed  Google Scholar 

  22. Makis W, Ciarallo A, Gotra A (2015) Clinical significance of parotid gland incidentalomas on 18F-FDG PET/CT. Clin Imaging 39:667–671. https://doi.org/10.1016/j.clinimag.2015.03.011

    Article  PubMed  Google Scholar 

  23. Üstün F, Tastekin E, Taş A, Altun GD (2019) The clinical significance of incidental parotid uptake in a PET/CT study: a diagnostic algorithm. Curr Med Imaging Rev 15:326–333. https://doi.org/10.2174/1573405614666171213160244

    Article  PubMed  Google Scholar 

  24. Mantsopoulos K, Koch M, Klintworth N, Zenk J, Iro H (2015) Evolution and changing trends in surgery for benign parotid tumors. Laryngoscope 125:122–127. https://doi.org/10.1002/lary.24837

    Article  PubMed  Google Scholar 

  25. Vaiman M, Abuita R, Jabarin B (2015) Selective deep lobe parotid surgery for benign tumors. Acta Otolaryngol 135:1319–1322. https://doi.org/10.3109/00016489.2015.1076170

    Article  PubMed  Google Scholar 

  26. Eisele DW, Wang SJ, Orloff LA (2010) Electrophysiologic facial nerve monitoring during parotidectomy. Head Neck 32:399–405. https://doi.org/10.1002/hed.21190

    Article  PubMed  Google Scholar 

  27. Dulguerov P, Marchal F, Lehmann W (1999) Postparotidectomy facial nerve paralysis: possible etiologic factors and results with routine facial nerve monitoring. Laryngoscope 109:754–762. https://doi.org/10.1097/00005537-199905000-00014

    Article  CAS  PubMed  Google Scholar 

  28. Terrell JE, Kileny PR, Yian C, Esclamado RM, Bradford CR, Pillsbury MS et al (1997) Clinical outcome of continuous facial nerve monitoring during primary parotidectomy. Arch Otolaryngol Head Neck Surg 123:1081–1087. https://doi.org/10.1001/archotol.1997.01900100055008

    Article  CAS  PubMed  Google Scholar 

  29. Witt RL (1998) Facial nerve monitoring in parotid surgery: the standard of care? Otolaryngol Head Neck Surg 119:468–470. https://doi.org/10.1016/s0194-5998(98)70103-2

    Article  CAS  PubMed  Google Scholar 

  30. Upton DC, McNamar JP, Connor NP, Harari PM, Hartig GK (2007) Parotidectomy: ten-year review of 237 cases at a single institution. Otolaryngol Head Neck Surg 136:788–792. https://doi.org/10.1016/j.otohns.2006.11.037

    Article  PubMed  Google Scholar 

  31. Ruohoalho J, Mäkitie AA, Aro K, Atula T, Haapaniemi A, Keski-Säntti H, Takala A, Bäck LJ (2017) Complications after surgery for benign parotid gland neoplasms: a prospective cohort study. Head Neck 39:170–176. https://doi.org/10.1002/hed.24496

    Article  PubMed  Google Scholar 

  32. Nouraei SA, Ismail Y, Ferguson MS, McLean NR, Milner RH, Thomson PJ, Welch AR (2008) Analysis of complications following surgical treatment of benign parotid disease. ANZ J Surg 78:134–138. https://doi.org/10.1111/j.1445-2197.2007.04388

    Article  PubMed  Google Scholar 

  33. Stenson KM, Mishell J, Toriumi DM (1991) Cystic hygroma of the parotid gland. Ann Otol Rhinol Laryngol 100:518–520. https://doi.org/10.1177/000348949110000617

    Article  CAS  PubMed  Google Scholar 

  34. Livesey JR, Soames JV (1992) Cystic lymphangioma in the adult parotid. J Laryngol Otol 106:566–568. https://doi.org/10.1017/s0022215100120171

    Article  CAS  PubMed  Google Scholar 

  35. Chinnakkulam Kandhasamy S, Ramasamy Raju T, Sahoo AK, Gunasekaran G (2018) Adult cystic lymphangioma of the parotid gland: an unwonted presentation. Cureus 10(5):2644. https://doi.org/10.7759/cureus.2644

    Article  Google Scholar 

  36. Liu J, Cheng LJ, Zhang Y, Song TH, Wang JW (2020) Rich fat hemangioma of the parotid gland in the adult. J Craniofac Surg 31:1054–1055. https://doi.org/10.1097/scs.0000000000006332

    Article  PubMed  Google Scholar 

  37. Madero-Visbal R, Milas Z (2014) The role of parotidectomy in Sjögren’s syndrome. Oral Maxillofac Surg Clin N Am 26:83–90. https://doi.org/10.1016/j.coms.2013.09.007

    Article  Google Scholar 

Download references

Funding

The authors did not receive support from any organization for the submitted work.

Author information

Authors and Affiliations

Authors

Contributions

HG: Conceptualization, Methodology, Data curation. Oİ: Formal analysis, Writing—original draft preparation, Methodology. YV: Writing—Reviewing and Editing. KG: Data curation, Supervision. MÜ: Writing—Reviewing and Editing, Supervision. OG: Data curation, Supervision. CÖ: Writing—Reviewing and Editing, Supervision, Methodology.

Corresponding author

Correspondence to Harun Gür.

Ethics declarations

Conflict of interest

All the authors declare no conflict of interest.

Ethics Approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of University Mersin (Date: 04.03.2020/No: 2020/209).

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gür, H., İsmi, O., Vayısoğlu, Y. et al. Results of 301 Parotidectomies: A Twenty-Year Experience of One Single Institution. Indian J Otolaryngol Head Neck Surg 75, 208–217 (2023). https://doi.org/10.1007/s12070-022-03157-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-022-03157-3

Keywords

Navigation