Abstract
Presentation with cervical lymphadenopathy would usually have an aetiology of neoplasm, infection or reactive cause. Dual pathology of regional metastasis with simultaneous occurrence of tuberculous lymphadenopathy is rather rare. Herein the authors present a case of primary occult carcinoma and tuberculous lymphadenopathy in an unfortunate patient. The reliability of fine-needle aspiration cytology as a first-line investigation, with alternative methods in approaching cervical lymphadenopathy, was further dissected.
Similar content being viewed by others
References
Wang WC, Chen JY, Chen YK, Lin LM (2009) Tuberculosis of the head and neck: a review of 20 cases. Oral Surg Oral Med Oral Pathol Oral RadiolEndod 107(3):381–386
Williams RG, Douglas-Jones T (1995) Mycobacterium marches back. J LaryngolOtol 109:5–13
Greco FA, Hainsworth JD (2011) Cancer of unknown primary site. In: DeVita VT, Lawrence TS, Rosenburg SA (eds) DeVite Hellman and Rosenberg’s cancer: principle and practice of oncology, 9th edn. Lippincott, Williams, and Wilkins, Philadelphia, PA, pp 2033–2051
Bussu F, Sali M, Gallus R et al (2015) HPV and EBV infections in neck metastases from occult primary squamous cell carcinoma: another virus-related neoplastic disease in the head and neck region. Ann SurgOncol 22:979–984. https://doi.org/10.1245/s10434-015-4808-5
Menon K, Bem C, Gouldesbrough D, Strachan DR (2007) A clinical review of 128 cases of head and neck tuberculosis presenting over a 10-year period in Bradford. UK J LaryngolOtol 121(4):362–368
Falagas ME, Kouranos VD, Athanassa Z, Kopterides P (2010) Tuberculosis and malignancy. QJM Int J Med 103(7):461–487
Lowe VJ, Delbeke D, Coleman RE (2003) Applications of PET in oncologic imaging. In: Colemen RE, Patton JA, Wackers FJ, Gotschalk A (eds) Diagnostic nuclear medicine, 4th edn. Philadelphia, Lippincot, pp 987–1014
Harkirat S, Anana SS, Indrajit LK, Dash AK (2008) Pictorial essay: PET/CT in tuberculosis. Indian J Radiol Imaging 18(2):141–147
Altuwairgi O, Baharoon S, Alkabab Y, Alsafi E, Almoweqel M, Al-Jahdali H (2014) Ultrasound-guided core biopsy in the diagnostic work-up of tuberculous lymphadenitis in Saudi Arabia, refining the diagnostic approach. Case series and review of literature. J Infect Public Health 7(5):371–376. https://doi.org/10.1016/j.jiph.2014.03.002
Allin D, David S, Jacob A, Mir N, Giles A, Gibbins N (2017) Use of core biopsy in diagnosing cervical lymphadenopathy: a viable alternative to surgical excisional biopsy of lymph nodes? Ann R CollSurgEngl 99(3):242–244
Acknowledgement
The author would like to thank the Director General of Health Malaysia for the permission to publish this paper
Funding
The authors declared that this study has received no financial support.
Author information
Authors and Affiliations
Contributions
SDS: Conceptualization, Methodology, Writing—Original Draft, Investigation, Visualization, Project administration. GJT Conceptualization, Methodology, Writing—Review & Editing, Visualization. ZAZA: Writing—Review & Editing, Supervision, Project administration. SA: Writing—Review & Editing, Supervision, Investigation.
Corresponding author
Ethics declarations
Conflict of interest
The authors have no conflict of interest to declare.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Subramaniam, S.D., Tuang, G.J., Zainal Abidin, Z.A. et al. Case Report: Metastatic Neck Nodes of Unknown Origin with Concurrent Tuberculous Lymphadenitis. Is Fine Needle Aspiration and Cytology (FNAC) Adequate?. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5888–5892 (2022). https://doi.org/10.1007/s12070-021-02497-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-021-02497-w