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Leiomyosarcoma of Mandible: A Diagnostic Dilemma; Case Report and Review of Literature

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Abstract

Leiomyosarcoma and its pleomorphic variant are rare entities in the head and neck region. Since they usually present as slow growing, discrete firm, and non-ulcerated painless mass, they seem to be deceptively benign and are thus misdiagnosed. Histopathological and immunohistochemical studies are the ways of getting a definitive diagnosis. Till date surgery has been the primary treatment but effectiveness of radiotherapy/chemotherapy is still questionable. Here, we describe a case of leiomyosarcoma in mandible along with discussion about the ways of diagnosis, its differentiation with its pleomorphic variant and their managements.

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References

  1. Yadav J, Bakshi J, Chouhan M, Modi R (2013) Head and neck leiomyosarcoma. Indian J Otolaryngol Head Neck Surg 65(1):1–5

    Article  Google Scholar 

  2. Marx RE, Stern D (2003) Oral and maxillofacial pathology. Quintessence, Chicago

    Google Scholar 

  3. Guillou L (2008) Pleomorphic sarcomas: subclassification, myogenic differentiation and prognosis. Diagn Histopathol 14(11):527–537

    Article  Google Scholar 

  4. Oda Y, Miyajima K, Kawaguchi KI, Tamiya S, Oshiro Y, Hachitanda Y, Oya M, Iwamoto Y, Tsuneyoshi M (2001) Pleomorphic leiomyosarcoma: clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and malignant fibrous histiocytoma. Am J Surg Pathol 25(8):1030–1038

    Article  CAS  Google Scholar 

  5. Patel K, French C, Khariwala SS, Rohrer M, Kademani D (2013) Intraosseous leiomyosarcoma of the mandible: a case report. J Oral Maxillofac Surg 71(7):1209–1216

    Article  Google Scholar 

  6. Gokavarapu S, Kumar KJ, Chander R, Murthy S (2014) Leiomyosarcoma of oral cavity: rare presentation in retromolar trigone. Oral Sci Int 11(2):76–79

    Article  Google Scholar 

  7. Marioni G, Bertino G, Mariuzzi L, Bergamin-Bracale AM, Lombardo M, Beltrami CA (2000) Laryngeal leiomyosarcoma. J Laryngol Otol 114(5):398–401

    Article  CAS  Google Scholar 

  8. Eilber FR, Eckardt J (1997) Surgical management of soft tissue sarcomas. Semin Oncol 24:526–533

    CAS  PubMed  Google Scholar 

  9. Nicolas MM, Tamboli P, Gomez JA, Czerniak BA (2010) Pleomorphic and dedifferentiated leiomyosarcoma: clinicopathologic and immunohistochemical study of 41 cases. Hum Pathol 41(5):663–671

    Article  CAS  Google Scholar 

  10. Cipriani NA, Kurzawa P, Ahmad RA, Deshpande V, Hornicek FJ, Mullen JT, Nielsen GP (2014) Prognostic value of myogenic differentiation in undifferentiated pleomorphic sarcomas of soft tissue. Hum Pathol 45(7):1504–1508

    Article  Google Scholar 

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Correspondence to Mihika Bala.

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Bala, M., Ray, A. & Saraf, A. Leiomyosarcoma of Mandible: A Diagnostic Dilemma; Case Report and Review of Literature. Indian J Otolaryngol Head Neck Surg 71 (Suppl 1), 848–851 (2019). https://doi.org/10.1007/s12070-019-01584-3

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  • DOI: https://doi.org/10.1007/s12070-019-01584-3

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