Skip to main content

Advertisement

SpringerLink
Log in

To Evaluate the Role of H. pylori in Patients with Chronic Recurrent Tonsillitis

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

The usual indication for surgical resection of tonsils is chronic recurrent tonsillitis. Literature also does not indicate the reason behind the fact that only part of the population suffers from recurrent chronic tonsillitis in spite being exposed to similar conditions. This was a prospective study, in which 50 tonsil biopsy samples obtained from chronic tonsillitis patients. Specimens were analysed with rapid urease broth test, HelicotecUT PLUS assay and Toluidine blue staining for presence of Helicobacter pylori. The age ranged from 4 to 34 years. The median age for patients with chronic recurrent tonsillitis was 9.5, 23 (46%) patients were male while 27 (54%) were female, presence of H. pylori by rapid urease broth test, HelicotecUT PLUS assay and Histopathology was 4%. Our analysis revealed that H. pylori did not significantly colonize the tonsils and does not play a role in the pathogenesis or development of chronic tonsillitis. The heterogeneity in study population and methodology may have contributed to the non significant results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Abbreviations

H. pylori :

Helicobacter pylori

h:

Hours

MALT:

Mucosa associated lymphoid tissue

mm:

Millimetre

min:

Minutes

Ltd:

Limited

GABHS:

Group A beta hemolytic streptococcus

References

  1. Arora S, Agrawal M, Nazmi M, Kapoor NK (2008) Histological study of routine tonsillectomy specimen. Indian J Otolaryngol Head Neck Surg 60:309–313

    Article  PubMed  PubMed Central  Google Scholar 

  2. Cammarota GA, Tursi L, Marinis De, Papa A, Valle D, Cuoco L et al (1997) Gastric mucosa-associated lymphoid tissue in autoimmune thyroid diseases. Scand J Gastroenterol 32(9):869–872

    Article  CAS  PubMed  Google Scholar 

  3. Pytko-Polonczyk J, Konturek SJ, Karczewska E, Bielański W, Kaczmarczyk-Stachowska A (1996) Oral cavity as permanent reservoir of Helicobacter pylori and potential source of re infection. J Physiol Pharmacol 47(1):121–129

    CAS  PubMed  Google Scholar 

  4. Kim N, Lim SH, Lee KH, You JY, Kim JM, Lee NR et al (2000) Helicobacter pylori in dental plaque and saliva. Korean J Intern Med 15(3):187–194

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Paradise JL, Bluestone CD, Bachman RZ et al (1984) Efficacy of tonsillectomy for recurrent throat infection in severely affected children. Results of parallel randomized and nonrandomized clinical trials. N Engl J Med 310:674–683

    Article  CAS  PubMed  Google Scholar 

  6. Khademi B, Imanieh MH, Gandomi B, Yeganeh F, Niknejad N (2005) Investigation of H. pylori colonization in adenotonsillectomy specimens by means of rapid urease (CLO) test. Iran J Med Sci 30(3):54–65

    Google Scholar 

  7. Peter Ochung O, Mugwe P, Masinde P, Waweru W (2015) The prevalence of H. pylori in tonsillar tissue of patients with adenotonsillar hypertrophy using Rapid Urease Test in a tertiary hospital in a sub Saharan country. Indian J Otolaryngol Head Neck Surg 67(3):223–226

    Article  Google Scholar 

  8. Woolford TJ, Hanif J, Washband S, Hari CK, Ganguli LA (1999) The effect of previous antibiotic therapy on the bacteriology of the tonsils in children. Int J Clin Pract 53(2):96–98

    CAS  PubMed  Google Scholar 

  9. Stoodley P, Debeer D, Longwell M, Nistico L, Hall-Stoodley L, Wenig B (2009) Tonsillolith: not just a stone but a living biofilm. Otolaryngol Head Neck Surg 141:316–321

    Article  PubMed  Google Scholar 

  10. Ramírez A, Peidrola D, López A, Martínez MD, Ros MJ, Corral JL, Arteaga E (1997) Beta-hemolytic streptococci in tonsil hypertrophy and recurrent tonsillitis. Enferm Infecc Microbiol Clin 15(6):315–318

    PubMed  Google Scholar 

  11. Zahedi MJ, Moghadam SD, Mosavi MA, Mirshekari T, Hayatbakhsh M (2009) Helicobacter pylori colonization in biopsies of the adenotonsillectomy specimens. Am J Appl Sci 6(12):2050–2053

    Article  CAS  Google Scholar 

  12. Kariya Shin, Okano Mitsuhiro, Nishizaki Kazunori (2014) An association between Helicobacter pylori and upper respiratory tract disease: fact or fiction? World J Gastroenterol 20(6):1470–1484

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Hwang MS, Forman SN, Kanter JA, Friedman M (2015) Tonsillar Helicobacter pylori colonization in chronic tonsillitis systematic review and meta-analysis. JAMA Otolaryngol Head Neck Surg 141(3):245–249

    Article  PubMed  Google Scholar 

  14. Sakonlaya D, Apisarnthanarak A, Yamada N, Tomtitchong P (2014) Modified toluidine blue: an alternative stain for Helicobacter pylori detection in routine diagnostic use and post-eradication confirmation for gastric cancer prevention. Asian Pac J Cancer Prev 15(16):6983–6987

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of ENT, Head and Neck Surgery, Meenakshi Medical College and Research Institute, Enathur, Kanchipuram, Tamil Nadu, 631552, India

    Suresh Mani, Assadi Rekha & Muthiah Kothanda Ramanujam Srinivasan

  2. Department of Pathology, Meenakshi Medical College and Research Institute, Kanchipuram, Tamil Nadu, 631552, India

    Venkatasubramanyam Bhanumathy

Authors
  1. Suresh Mani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Assadi Rekha
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Muthiah Kothanda Ramanujam Srinivasan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Venkatasubramanyam Bhanumathy
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Suresh Mani.

Ethics declarations

Conflict of Interest

All authors declare that they have no conflict of interest.

Funding

No funding was received for this study

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Ethical Approval

We have received ethical clearance from our institute ethical committee before starting the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mani, S., Rekha, A., Srinivasan, M.K.R. et al. To Evaluate the Role of H. pylori in Patients with Chronic Recurrent Tonsillitis. Indian J Otolaryngol Head Neck Surg 71, 254–258 (2019). https://doi.org/10.1007/s12070-018-1313-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-018-1313-8

Keywords

Search

Navigation