Skip to main content
SpringerLink
Log in

Antibacterial, antioxidant properties of Solanum trilobatum and sodium hydroxide-mediated magnesium oxide nanoparticles: a green chemistry approach

  • Published:
Bulletin of Materials Science Aims and scope Submit manuscript

Abstract

A comparative study of Solanum trilobatum-mediated magnesium oxide (St-MgO) nanoparticles (NPs) and sodium hydroxide-mediated MgO (Che-MgO) NPs are synthesized using magnesium nitrate precursor. The characterization analyses, such as ultraviolet–visible spectroscopy (UV–Vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), energy-dispersive X-ray diffraction (EDX), scanning electron microscopy (SEM) and particle-size analysis were carried out. To determine the antioxidant activity of MgO NPs by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and antibacterial activity against Escherichia coli (MTCC: 912), Bacillus subtilis (MTCC: 121) and Streptococcus pyogenes (MTCC: 1925), was performed by the well-diffusion method. The UV–Vis analysis of St-MgO, Che-MgO confirmed the formation of MgO NPs that have a broad absorption peak at 362 and 374 nm, respectively. IR spectrum of synthesized St-MgO and Che-MgO exhibits a high-intensity band at 440 and 460 \(\text {cm}^{-1}\), respectively. XRD analysis indicates that synthesized St-MgO, Che-MgO were crystal in nature and EDX confirmed the composition of MgO-NPs. SEM analysis revealed that St-MgO and Che-MgO NPs were spherical in shape without aggregation. Particle-size analysis confirmed that the average particle sizes of St-MgO and Che-MgO NPs were 30 and 42 nm, respectively. DPPH assay of St-MgO NPs has higher absorbance value, which indicates the high antioxidant capacity compared with ascorbic acid. St-MgO NPs are effective against bacterial pathogens, such as E. coli (16.66 ± 0.66), B. subtilis (16.00 ± 0.88) and S. pyogenes (13.66 ± 2.08) at 100 mg \(\hbox {ml}^{-1}\) concentration when compared with Che-MgO and the control (\(P<0.001\)). Thus, the result suggested that safer use of biologically synthesized MgO NPs can act as effective antioxidant and antibacterial agents in the field of biomedicine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Alaa Y G, Tawfiq M A, Akl M M and Muhand W A 2017 ARPN J. Agric. Biol. Sci. 10 293

    Google Scholar 

  2. Al-Gaashani R, Radiman S, Al-Douri Y, Tabet N and Daud A R 2012 J. Alloys Compd. 52 71

    Article  Google Scholar 

  3. Al-Hazmi F, Alnowaiser F, Al-Ghamdi A A, Aly M M, Al-Tuwirqi R M and El-Tantawy F 2012 Superlattices Microstruct. 52 200

    Article  CAS  Google Scholar 

  4. Alvarado E, Torres-Martinez L M and Fuentes A F 2000 Polyhedron 19 2345

    Article  CAS  Google Scholar 

  5. Bhatte K D, Sawant D N, Watile R A and Bhanage B M 2012 Mater. Lett. 69 66

    Article  CAS  Google Scholar 

  6. Doss A, Muhamed M H and Dhanabalan R 2009 Indian J. Sci. Tech. 2 41

    CAS  Google Scholar 

  7. Ganapathi R K, Ashok C H, Venkateswara R K, Shilpa Chakra C H and Akshaykranth A 2015 Int. J. Adv. Res. Phys. Sci. 2 1

    Google Scholar 

  8. Huang L, Li D Q, Lin Y J, Evans D G and Duan X 2005 Chin. Sci. Bull. 50 514

    Article  CAS  Google Scholar 

  9. Jawhar M, Amalan R G and Jeyaseelan M 2004 Plant Tissue Cult. Biotechnol. 14 107

    Google Scholar 

  10. Kanchana D, Jayanthi M, Kanchana D, Saranraj P and Sujitha D 2013 Int. J. Microbiol. Res. 4 300

    CAS  Google Scholar 

  11. Krishnamoorthy K, Manivannan G, Kim S J, Jeyasubramanian K and Premanathan M 2012 J. Nanoparticle Res. 14 1063

    Article  Google Scholar 

  12. Kumar D, Reddy Yadav L S, Lingaraju K, Manjunath K, Suresh D, Prasad D et al 2015 AIP Conf. Proc. 1665 050145

    Article  Google Scholar 

  13. Li Y J, Li D Q, Wang G, Huang L and Duan X 2005 J. Mater. Sci. Mater. Med. 16 53

    Article  Google Scholar 

  14. Vanaja M, Paulkumar K, Baburaja M, Rajeshkumar S, Gnanajobitha G, Malarkodi C et al 2014 Bioinorg. Chem. Appl. 2014 8

    Article  Google Scholar 

  15. Marina Z, Mariana P, Thiele F B, Aline A B, Robson B F, Michel M M et al 2012 Molecules 17 12560

    Article  Google Scholar 

  16. Narendhran S, Rajiv P, Vanathi P and Rajeshwari S 2014 Int. J. Pharm. Pharm. Sci. 6 319

    CAS  Google Scholar 

  17. Narendhran S, Rajiv P and Rajeshwari S 2016 Bull. Mater. Sci. 39 1

    Article  CAS  Google Scholar 

  18. Pacholski C, Kornowski A and Weller H 2002 Angew. Chem. Int. Ed. 41 1188

    Article  CAS  Google Scholar 

  19. Palanisamy G and Pazhanivel T 2017 Int. Res. J. Eng. Tech. 4 137

    Google Scholar 

  20. Raghupati R K, Koodali R T and Manna A C 2011 Langmuir 27 4020

    Article  Google Scholar 

  21. Rai M and Ingle A 2012 Appl. Microbiol. Biotechnol. 94 287

    Article  CAS  Google Scholar 

  22. Rajeshwari S, Rahman P K S M, Rajiv P, Narendhran S and Venckatesh R 2014 Spectrochim. Acta Part A 129 255

    Article  Google Scholar 

  23. Rajiv P, Rajeshwari S and Venckatesh R 2013 Spectrochim. Acta Part A 112 384

    Article  CAS  Google Scholar 

  24. Renata D 2016 Iran. J. Sci. Technol. A 1 9

    Google Scholar 

  25. Selvam N C S, Kumar R T, Kennedy L J and Vijaya J J 2011 J. Alloys Compd. 509 9809

    Article  CAS  Google Scholar 

  26. Shahjahan M, Sabitha K E, Jamu M and Shyamala Devi C S 2004 Indian J. Med. Res. 120 194

    CAS  Google Scholar 

  27. Sri Vishnupriya R, Narendhran S and Rajeshwari S 2016 Bull. Mater. Sci. 39 361

    Article  Google Scholar 

  28. Stoimenov P K, Klinger R L, Marchin G L and Klabunde K J 2002 Langmuir 18 6679

    Article  CAS  Google Scholar 

  29. Sundrarajan M, Suresh J and Gandhi R R 2012 Dig. J. Nanomater. Biostruct. 7 983

    Google Scholar 

Download references

Acknowledgements

We acknowledge the management of Sri Krishna Arts and Science College, Coimbatore, Tamil Nadu, India, for providing necessary facilities to carry out this study.

Author information

Authors and Affiliations

  1. Department of Bioscience, Sri Krishna Arts and Science College, Sugunapuram, Kuniamuthur P.O., Coimbatore, 641008, India

    S Narendhran, M Manikandan & P Baby Shakila

Authors
  1. S Narendhran
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M Manikandan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P Baby Shakila
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S Narendhran.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Narendhran, S., Manikandan, M. & Shakila, P.B. Antibacterial, antioxidant properties of Solanum trilobatum and sodium hydroxide-mediated magnesium oxide nanoparticles: a green chemistry approach. Bull Mater Sci 42, 133 (2019). https://doi.org/10.1007/s12034-019-1811-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s12034-019-1811-7

Keywords

Search

Navigation